Serum Colony Stimulating Factor Levels in Irradiated Germfree and Conventional GFW Mice

Alec Morley; Peter Quesenberry; Patricia Bealmear; Frederick Stohlman; Raphael Wilson

doi:10.3181/00379727-140-36484

Serum Colony Stimulating Factor Levels in Irradiated Germfree and Conventional GFW Mice

Alec Morley, Peter Quesenberry, Patricia Bealmear, Frederick Stohlman, Raphael Wilson

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

Germfree and conventional CFW mice were evaluated for elevations in serum CSF levels at varying time intervals after 850 R whole body irradiation. Conventional mice showed elevations of CSF levels on Days 6–9 while sera from germfree mice were inactive on Days 1–10. The data suggests that the bacterial flora of the gut play a role in the elevations of serum CSF seen after irradiation. The technical assistance of Mrs. Mildred Rosen-field is gratefully acknowledged.

Original language	English
Pages (from-to)	478-480
Number of pages	3
Journal	Proceedings of the Society for Experimental Biology and Medicine
Volume	140
Issue number	2
DOIs	https://doi.org/10.3181/00379727-140-36484
Publication status	Published - Jun 1972
Externally published	Yes

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abstract = "Germfree and conventional CFW mice were evaluated for elevations in serum CSF levels at varying time intervals after 850 R whole body irradiation. Conventional mice showed elevations of CSF levels on Days 6–9 while sera from germfree mice were inactive on Days 1–10. The data suggests that the bacterial flora of the gut play a role in the elevations of serum CSF seen after irradiation. The technical assistance of Mrs. Mildred Rosen-field is gratefully acknowledged.",

author = "Alec Morley and Peter Quesenberry and Patricia Bealmear and Frederick Stohlman and Raphael Wilson",

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AU - Stohlman, Frederick

AU - Wilson, Raphael

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AB - Germfree and conventional CFW mice were evaluated for elevations in serum CSF levels at varying time intervals after 850 R whole body irradiation. Conventional mice showed elevations of CSF levels on Days 6–9 while sera from germfree mice were inactive on Days 1–10. The data suggests that the bacterial flora of the gut play a role in the elevations of serum CSF seen after irradiation. The technical assistance of Mrs. Mildred Rosen-field is gratefully acknowledged.

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Serum Colony Stimulating Factor Levels in Irradiated Germfree and Conventional GFW Mice

Abstract

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