Serum from a subset of patients with chronic lymphocytic leukemia and large local reactions to mosquito bites induces upregulation of CD63 surface expression on basophils in atopic donors

Jamma Li, Oliver Giles Best, Stephen P. Mulligan, Suran Loshana Fernando

Research output: Contribution to journalLetterpeer-review

4 Citations (Scopus)

Abstract

Reactions to mosquito bites are immunological reactions that are due to sensitization to mosquito salivary proteins. Large local reactions (LLRs) are areas of erythema and swelling from 2 to over 10 cm, which develop within a few hours of the bite, progress over 8–12 h, and resolve in 3–10 d [Figure 1(A) LLRs are painful and may cause significant distress. They seldom occur in adults, however, certain adult populations have increased prevalence of LLRs including those with chronic lymphocytic leukemia (CLL). Data suggest that prevalence in CLL varies between 2 and 45%...
Original languageEnglish
Pages (from-to)2417-2420
Number of pages4
JournalLeukemia & lymphoma
Volume57
Issue number10
DOIs
Publication statusPublished - 2 Oct 2016
Externally publishedYes

Keywords

  • lymphocytic leukemia
  • mosquito bite
  • basophils

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