Severe falciparum malaria in five soldiers from East Timor: A case series and literature review

P. G. Blum, D. Stephens

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

Despite chemoprophylaxis, malaria remains a serious threat for large numbers of non-immune soldiers deployed in endemic areas. Five adult cases of severe falciparum malaria are reported. Three cases were complicated by multiorgan failure and one of these patients died from cerebral malaria. These cases serve to highlight issues, in an Australian intensive care unit, associated with the management of severe malaria, an uncommon disease in our country. The need for rapid diagnosis and commencement of appropriate treatment is paramount in preventing further morbidity and mortality. Understanding and management of malaria continues to evolve rapidly. The pathophysiology of acute lung injury, shock and brain injury associated with malaria are examined in light of recent research. This article discusses the current controversies of exchange blood transfusion and the use of the new artemisinin derivatives.

Original languageEnglish
Pages (from-to)426-434
Number of pages9
JournalAnaesthesia and Intensive Care
Volume29
Issue number4
DOIs
Publication statusPublished - Aug 2001
Externally publishedYes

Keywords

  • Acute respiratory distress syndrome
  • Cerebral malaria
  • Exchange blood transfusion
  • Intensive care: Shock
  • Malaria: Plasmodium falciparum

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