TY - JOUR
T1 - Sex and gender as predictors for allograft and patient-relevant outcomes after kidney transplantation
AU - Jayanti, Sumedh
AU - Beruni, Nadim A.
AU - Chui, Juanita Noeline
AU - Deng, Danny
AU - Liang, Amy
AU - Chong, Anita
AU - Craig, Jonathan C.
AU - Foster, Bethany
AU - Howell, Martin
AU - Kim, Siah
AU - Sapir-Pichhadze, Ruth
AU - Mannon, Roslyn B.
AU - Scholes-Robertson, Nicole
AU - Strauss, Alexandra
AU - Tong, Allison
AU - West, Lori
AU - Cooper, Tess E.
AU - Wong, Germaine
PY - 2022/2/28
Y1 - 2022/2/28
N2 - Objectives: This is a protocol for a Cochrane Review (prognosis). The objectives are as follows:. To evaluate the prognostic effect of the recipient's (i) sex and gender separately (ii) gender as an independent predictor of patient-relevant outcomes at any time period following kidney or SPK transplantation () and explore sources of heterogeneity. We aim to evaluate this prognostic effect by (a) clearly defining the relationship between recipient sex/gender and post-transplantation outcomes, which would involve identifying reasons for variations between sexes and genders, and then (b) quantifying the magnitude of this relationship. 1 PICOTS summary of "Sex and gender as predictors for allograft and patient relevant outcomes after kidney transplantation" (Table presented.) "Criteria for Prognostic Reviews: Population, Index (prognostic factor), Comparator, Outcomes, Timing, Setting (PICOTS)" (Moons 2014). Investigation of sources of heterogeneity between studies Sources of heterogeneity may exist between studies that can have an impact on outcomes. We will explore potential sources, which may include patient age, self-reported ethnicity, country of transplantation, transplant era, living versus deceased donor transplantation, definitions and units used for outcomes, quality of the study, and the indication for kidney transplantation.
AB - Objectives: This is a protocol for a Cochrane Review (prognosis). The objectives are as follows:. To evaluate the prognostic effect of the recipient's (i) sex and gender separately (ii) gender as an independent predictor of patient-relevant outcomes at any time period following kidney or SPK transplantation () and explore sources of heterogeneity. We aim to evaluate this prognostic effect by (a) clearly defining the relationship between recipient sex/gender and post-transplantation outcomes, which would involve identifying reasons for variations between sexes and genders, and then (b) quantifying the magnitude of this relationship. 1 PICOTS summary of "Sex and gender as predictors for allograft and patient relevant outcomes after kidney transplantation" (Table presented.) "Criteria for Prognostic Reviews: Population, Index (prognostic factor), Comparator, Outcomes, Timing, Setting (PICOTS)" (Moons 2014). Investigation of sources of heterogeneity between studies Sources of heterogeneity may exist between studies that can have an impact on outcomes. We will explore potential sources, which may include patient age, self-reported ethnicity, country of transplantation, transplant era, living versus deceased donor transplantation, definitions and units used for outcomes, quality of the study, and the indication for kidney transplantation.
KW - Sex
KW - Gender
KW - Kidney Transplantation
UR - http://www.scopus.com/inward/record.url?scp=85125452795&partnerID=8YFLogxK
U2 - 10.1002/14651858.CD014966
DO - 10.1002/14651858.CD014966
M3 - Review article
AN - SCOPUS:85125452795
SN - 1465-1858
VL - 2022
JO - Cochrane Database of Systematic Reviews
JF - Cochrane Database of Systematic Reviews
IS - 2
M1 - CD014966
ER -