Silica Nanopills for Targeted Anticancer Drug Delivery

María Alba, Bahman Delalat, Pilar Formentín, Mary-Louise Rogers, Lluís Marsa, Nicholas Nicholas

    Research output: Contribution to journalArticlepeer-review

    12 Citations (Scopus)


    Multifunctional SiO2 microtubes for targeted drug delivery are produced with precise control over shape and size by combining lithography and electrochemical etching. The hollow core is loaded with a lipophilic anticancer drug generating nanopills and an antibody is conjugated to the external surface for cancer cell targeting. Results demonstrate selective killing of neuroblastoma cells that express the cognate receptor.

    Original languageEnglish
    Pages (from-to)4626-4631
    Number of pages6
    Issue number36
    Publication statusPublished - 1 Sep 2015


    • antibodies
    • cancer therapy
    • drug delivery
    • microtubes
    • porous silicon


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