Silica Nanopills for Targeted Anticancer Drug Delivery

María Alba, Bahman Delalat, Pilar Formentín, Mary-Louise Rogers, Lluís Marsa, Nicholas Nicholas

    Research output: Contribution to journalArticle

    10 Citations (Scopus)

    Abstract

    Multifunctional SiO2 microtubes for targeted drug delivery are produced with precise control over shape and size by combining lithography and electrochemical etching. The hollow core is loaded with a lipophilic anticancer drug generating nanopills and an antibody is conjugated to the external surface for cancer cell targeting. Results demonstrate selective killing of neuroblastoma cells that express the cognate receptor.

    Original languageEnglish
    Pages (from-to)4626-4631
    Number of pages6
    JournalSmall
    Volume11
    Issue number36
    DOIs
    Publication statusPublished - 2015

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  • Cite this

    Alba, M., Delalat, B., Formentín, P., Rogers, M-L., Marsa, L., & Nicholas, N. (2015). Silica Nanopills for Targeted Anticancer Drug Delivery. Small, 11(36), 4626-4631. https://doi.org/10.1002/smll.201402930