Sleep Apnea Cardiovascular Clinical Trials - Current Status and Steps Forward: The International Collaboration of Sleep Apnea Cardiovascular Trialists.

Daniel Gottlieb, Sonya Craig, Geraldo Lorenzi, Emma Heeley, Susan Redline, Ronald McEvoy, Joaquín Durán-Cantolla

    Research output: Contribution to journalArticle

    26 Citations (Scopus)

    Abstract

    Sleep apnea is a common chronic disease that is associated with coronary heart disease, stroke, heart failure and mortality, although the ability of sleep apnea treatment to reduce cardiovascular morbidity and mortality has not been demonstrated. In contrast to patients seeking treatment in sleep disorders centers, as many as half of individuals with moderate to severe sleep apnea in the general population do not report excessive sleepiness; however, if treatment of sleep apnea were shown to reduce cardiovascular disease risk, this would provide a strong rationale for treatment of sleep apnea even in the absence of daytime sleepiness. This article summarizes the status of clinical trials evaluating the potential cardiovascular benefits of sleep apnea treatment and discusses the challenges of conducting such trials, and introduces the International Collaboration of Sleep Apnea Cardiovascular Trialists (INCOSACT), a clinical research collaboration formed to foster cardiovascular sleep research.

    Original languageEnglish
    Pages (from-to)975-980
    Number of pages6
    JournalSleep
    Volume36
    Issue number7
    DOIs
    Publication statusPublished - 1 Jul 2013

    Keywords

    • Cardiovascular disease
    • Clinical trials
    • Sleep apnea

    Fingerprint Dive into the research topics of 'Sleep Apnea Cardiovascular Clinical Trials - Current Status and Steps Forward: The International Collaboration of Sleep Apnea Cardiovascular Trialists.'. Together they form a unique fingerprint.

  • Cite this