Slow tight binding inhibition of CYP17A1 by abiraterone redefines its kinetic selectivity and dosing regimen

Eleanor Jing Yi Cheong, Pramod C. Nair, Rebecca Wan Yi Neo, Ho Thanh Tu, Fu Lin, Edmund Chiong, Kesavan Esuvaranathan, Hao Fan, Russell Szmulewitz, Cody J. Peer, William D. Figg, Christina Li Lin Chai, John O. Miners, Eric Chun Yong Chan

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    Medicine & Life Sciences