Solitary calcifying fibrous tumour of the pleura: A case report and literature review

Harry James Gaffney, Sonja Klebe, Kais Kasem, Sarita Prabhakaran

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Calcifying fibrous tumours of the pleura (CFTPs) are extremely rare benign tumours with uncertain aetiology, with only 34 cases, including this one, reported worldwide to date. CFTPs commonly originate from subcutaneous and deep soft tissues of the gastrointestinal tract and pleura. It is essential to differentiate CFTP from other pleural intrathoracic masses that present similarly but are challenging with radiological imaging alone. As a result, excision via surgical intervention alongside immunohistological and histological assessment is the current best method for definitive diagnosis. Due to the significantly low incidence of CFTP, extensive sample studies for further research are currently not possible. As a result, all cases of CFTP should be reported to help improve future research in diagnostic accuracy and understanding of pathogenicity and aetiology. We are reporting a case of an incidentally detected CFTP on CT in a 30-year-old female.

Original languageEnglish
Article number300724
Number of pages5
JournalHuman Pathology Reports
Publication statusPublished - Nov 2023


  • Benign
  • Calcifying fibrous tumour
  • CFTP
  • Pleura


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