Abstract
Liquid biopsies are emerging as a fast and non-invasive method to diagnose and monitor a variety of diseases. One option for prostate cancer detection is capturing cancer specific exosomes from urine. Yet, exosomes isolation is difficult because they are sub-micron entities within a complex mixture of cells and metabolites also present in urine. Here, we present the use of spiral inertial microfluidics with capture reservoirs as a passive separation method of micron sized particles followed by nanoparticles surface immobilization. The capture reservoir integrated downstream of the spiral contains a plasma polymerized polyoxazoline coating acting as a capture and sensing platform.
| Original language | English |
|---|---|
| Title of host publication | MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
| Place of Publication | San Diego |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 1187-1188 |
| Number of pages | 2 |
| Volume | 1 of 3 |
| ISBN (Electronic) | 9781733419031 |
| ISBN (Print) | 9781713855736 |
| Publication status | Published - 2021 |
| Externally published | Yes |
| Event | 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2021) - Palm Springs, Virtual, United States Duration: 10 Oct 2021 → 14 Oct 2021 Conference number: 25th https://www.microtasconferences.org/microtas2021/ (Conference description) |
Conference
| Conference | 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2021) |
|---|---|
| Abbreviated title | MicroTAS 2021 |
| Country/Territory | United States |
| City | Palm Springs, Virtual |
| Period | 10/10/21 → 14/10/21 |
| Internet address |
|
Keywords
- Inertial Microfluidics
- Microfluidic Systems
- Plasma Polymers
- Polyoxazolines
