Stability of electrically induced-polarization in poly (L-lactic) acid for bone regeneration

This paper describes the decay kinetics of electrically induced polarization of poly(L-lactic) acid (PLLA) via piezoresponse force microscopy. Two crystalline forms of PLLA (α and α′) were electrically poled at different temperatures (room and above glass transition). Poling at temperatures above glass transition allowed obtaining polarization stable up to 10 days for both forms. This period is enough to trigger and maintain proteins adhesion and cells proliferation, if PLLA is used as a platform for tissue growth. When poled at room temperature, both structures lose polarization after a short time (minutes to hours) being polarization in α PLLA stable for longer time.