Standardization of Nomenclature for Ocular Tuberculosis: Results of Collaborative Ocular Tuberculosis Study (COTS) Workshop

Rupesh Agrawal, Aniruddha Agarwal, Douglas A. Jabs, Aera Kee, Ilaria Testi, Sarakshi Mahajan, Peter J. McCluskey, Amod Gupta, Alan Palestine, Alastair Denniston, Alay Banker, Alessandro Invernizzi, Alex Fonollosa, Aman Sharma, Amitabh Kumar, Andre Curi, Annabelle Okada, Ariel Schlaen, Arnd Heiligenhaus, Atul KumarAvinash Gurbaxani, Bahram Bodaghi, Bulbul Islam Shah, Careen Lowder, Christoph Tappeiner, Cristina Muccioli, Daniel Vitor Vasconcelos-Santos, Debra Goldstein, Digambar Behra, Dipankar Das, Dorine Makhoul, Edoardo Baglivo, Ekaterina Denisova, Elisabetta Miserocchi, Ester Carreno, Fatma Asyari, Francesco Pichi, H. Nida Sen, Harvey Uy, Heloisa Nascimento, Ilknur Tugal-Tutkun, J. Fernando Arevalo, Janet Davis, Jennifer Thorne, Joyce Hisae Yamamoto, Justine Smith, Justus G. Garweg, Jyotirmay Biswas, Kalpana Babu, Kanika Aggarwal, Luca Cimino, Lucia Kuffova, Mamta Agarwal, Manfred Zierhut, Manisha Agarwal, Marc De Smet, Maria Sofia Tognon, Marie Helene Errera, Marion Munk, Mark Westcott, Masoud Soheilian, Massimo Accorinti, Moncef Khairallah, Myhanh Nguyen, Onn Minn Kon, Padmamalini Mahendradas, Peizeng Yang, Piergiorgio Neri, Pinar Ozdal, Radgonde Amer, Richard Lee, Rina La Distia Nora, Romi Chhabra, Rubens Belfort, Salil Mehta, Samir Shoughy, Saurabh Luthra, Shelina Oli Mohamed, Soon Phaik Chee, Soumyava Basu, Stephen Teoh, Sudha Ganesh, Talin Barisani-Asenbauer, Yan Guex-Crosier, Yılmaz Ozyazgan, Yonca Akova, Zohar Habot-Wilner, John Kempen, Quan Dong Nguyen, Carlos Pavesio, Vishali Gupta, Collaborative Ocular Tuberculosis Study (COTS) Group

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Abstract

Purpose: To standardize a nomenclature system for defining clinical phenotypes, and outcome measures for reporting clinical and research data in patients with ocular tuberculosis (OTB). Methods: Uveitis experts initially administered and further deliberated the survey in an open meeting to determine and propose the preferred nomenclature for terms related to the OTB, terms describing the clinical phenotypes and treatment and reporting outcomes. Results: The group of experts reached a consensus on terming uveitis attributable to tuberculosis (TB) as tubercular uveitis. The working group introduced a SUN-compatible nomenclature that also defines disease “remission” and “cure”, both of which are relevant for reporting treatment outcomes. Conclusion: A consensus nomenclature system has been adopted by a large group of international uveitis experts for OTB. The working group recommends the use of standardized nomenclature to prevent ambiguity in communication and to achieve the goal of spreading awareness of this blinding uveitis entity.

Original languageEnglish
Number of pages11
JournalOcular Immunology and Inflammation
Early online date10 Dec 2019
DOIs
Publication statusE-pub ahead of print - 10 Dec 2019

Keywords

  • Antitubercular therapy
  • Ocular tuberculosis
  • remission
  • tubercular uveitis
  • tuberculous
  • uveitis

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