Strontium-doped hardystonite plasma sprayed coatings with robust antimicrobial activity

D. Q. Pham, S. Gangadoo, Z. Lu, C. C. Berndt, E. T. Newsom, H. Zreiqat, V. K. Truong, A. S.M. Ang

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

A strontium-doped hardystonite (Sr-HT) bioceramic, in bulk form, demonstrates excellent bioactivity for bone regeneration with high fracture toughness and compressive strength. This work examines the antibacterial and mechanical properties of Sr-HT coatings on an alpha-beta titanium alloy with a high specific strength and excellent corrosion resistance (Ti-6Al-4V) produced by atmospheric plasma spray (APS) as the deposition coating technique. A hydroxyapatite (HAp) APS coating, a commercial bioceramic coating, is chosen as the control. The in-situ observation showed that Sr-HT powders experience temperatures during plasma processing that exceeded their melting point to form a coating well adhered to the substrate. It was demonstrated that the Sr-HT coating possessed superior antibacterial properties against Gram-positive methicillin-resistant Staphylococcus aureus (MRSA) and Gram-negative Pseudomonas aeruginosa. In addition, the Sr-HT coating exhibits a uniform distribution of hardness and elastic moduli, higher nanohardness and elastic moduli compared to the equivalent properties of the HAp coating. Moreover, the Sr-HT coating outperforms the HAp coating regarding scratch and wear resistance. The bonding and shear strength of the Sr-HT coating are higher than the values required for orthopedic implant coatings. The Sr-HT coating also allows efficient zinc, silicon and strontium ions release when immersed in cell culture media. In summary, the antibacterial capabilities and the mechanical properties of the Sr-HT APS coating exceed those of the commercial HAp APS coating. Therefore, Sr-HT APS coatings are candidates for bioceramic coating applications in orthopedic implants.

Original languageEnglish
Article number100822
Number of pages16
JournalMaterials Today Chemistry
Volume24
DOIs
Publication statusPublished - Jun 2022

Keywords

  • Antibacterial
  • Hardystonite
  • Mechanical properties
  • Nanoindentations
  • Plasma sprayed coatings

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