Studies on the origin and excretion of serum α-amylase in the mouse

Peter I. MacKenzie, Michael Messer

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)


1. 1. Partially purified amylase preparations of various mouse tiflaes were studied by cellulose acetate electrophoresis. The liver and serum contained predominantly an amylase variant electrophoretically identical with parotid amylase, but urine contained only the pancreatic type. 2. 2. Mouse serum amylase activity was markedly reduced by partial hepatectomy but not by sialadenectomy. 3. 3. Intravenously injected mouse pancreatic amylase rapidly disappeared from the serum and appeared in the urine; parotid amylase also disappeared from the serum, but little of it appeared in the urine. 4. 4. It is concluded that mouse liver secretes amylase of both pancreatic and parotid types into the blood, but only the pancreatic type is excreted.

Original languageEnglish
Pages (from-to)103-106
Number of pages4
JournalComparative Biochemistry and Physiology -- Part B: Biochemistry and
Issue number1
Publication statusPublished - 1976
Externally publishedYes


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