Subcutaneous Heparin to Prevent Venous Thrombosis

Lawrence Martin, A. S. Gallus, J. Hirsh

Research output: Contribution to journalLetterpeer-review


To the Editor: The results by Gallus et al.1 are open to major criticism in that their study was not double-blinded. They state (in the results section), “surgeons were unaware of which patients were treated with heparin,” so presumably the postoperative care, as well as the care of medical patients, and all fibrinogen scans, was handled by those who knew which patients were on heparin. The medical literature is replete with studies of heparin prophylaxis, almost all of which can be faulted for their clinical design. This shortcoming has been pointed out for myocardial infarction.2 In such a controversial area.

Original languageEnglish
Pages (from-to)1245
Number of pages1
JournalNew England Journal of Medicine
Issue number23
Publication statusPublished - 7 Jun 1973
Externally publishedYes


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