Abstract
The presence, distribution and origin of substance P immunoreactive axons in the rat iris and cornea were investigated in whole mount preparations. A dense network of substance P immunoreactive was found throughout the iris but not in the ciliary body. In the cornea, substance P immunoreactive axons were found in the substantia propria, in the subepithelial layer and in the corneal epithelium. Following electrocoagulation of the opthalmic nerve, most of the substance P immunoreactive axons in the iris and cornea disappeared. No changes in the substance P immunoreactive axons occurred after removal of the superior cervical ganglion. It is concluded that the iris and the cornea are supplied by sensory nerves containing substance P immunoreactivity.
| Original language | English |
|---|---|
| Pages (from-to) | 243-249 |
| Number of pages | 7 |
| Journal | Neuroscience letters |
| Volume | 23 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 29 May 1981 |