Substance P immunoreactive sensory nerves supply the rat iris and cornea

A. Miller; M. Costa; J. B. Furness; I. W. Chubb

doi:10.1016/0304-3940(81)90005-7

Substance P immunoreactive sensory nerves supply the rat iris and cornea

A. Miller, M. Costa, J. B. Furness, I. W. Chubb

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Abstract

The presence, distribution and origin of substance P immunoreactive axons in the rat iris and cornea were investigated in whole mount preparations. A dense network of substance P immunoreactive was found throughout the iris but not in the ciliary body. In the cornea, substance P immunoreactive axons were found in the substantia propria, in the subepithelial layer and in the corneal epithelium. Following electrocoagulation of the opthalmic nerve, most of the substance P immunoreactive axons in the iris and cornea disappeared. No changes in the substance P immunoreactive axons occurred after removal of the superior cervical ganglion. It is concluded that the iris and the cornea are supplied by sensory nerves containing substance P immunoreactivity.

Original language	English
Pages (from-to)	243-249
Number of pages	7
Journal	Neuroscience letters
Volume	23
Issue number	3
DOIs	https://doi.org/10.1016/0304-3940(81)90005-7
Publication status	Published - 29 May 1981

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title = "Substance P immunoreactive sensory nerves supply the rat iris and cornea",

abstract = "The presence, distribution and origin of substance P immunoreactive axons in the rat iris and cornea were investigated in whole mount preparations. A dense network of substance P immunoreactive was found throughout the iris but not in the ciliary body. In the cornea, substance P immunoreactive axons were found in the substantia propria, in the subepithelial layer and in the corneal epithelium. Following electrocoagulation of the opthalmic nerve, most of the substance P immunoreactive axons in the iris and cornea disappeared. No changes in the substance P immunoreactive axons occurred after removal of the superior cervical ganglion. It is concluded that the iris and the cornea are supplied by sensory nerves containing substance P immunoreactivity.",

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AU - Miller, A.

AU - Costa, M.

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AU - Chubb, I. W.

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Y1 - 1981/5/29

N2 - The presence, distribution and origin of substance P immunoreactive axons in the rat iris and cornea were investigated in whole mount preparations. A dense network of substance P immunoreactive was found throughout the iris but not in the ciliary body. In the cornea, substance P immunoreactive axons were found in the substantia propria, in the subepithelial layer and in the corneal epithelium. Following electrocoagulation of the opthalmic nerve, most of the substance P immunoreactive axons in the iris and cornea disappeared. No changes in the substance P immunoreactive axons occurred after removal of the superior cervical ganglion. It is concluded that the iris and the cornea are supplied by sensory nerves containing substance P immunoreactivity.

AB - The presence, distribution and origin of substance P immunoreactive axons in the rat iris and cornea were investigated in whole mount preparations. A dense network of substance P immunoreactive was found throughout the iris but not in the ciliary body. In the cornea, substance P immunoreactive axons were found in the substantia propria, in the subepithelial layer and in the corneal epithelium. Following electrocoagulation of the opthalmic nerve, most of the substance P immunoreactive axons in the iris and cornea disappeared. No changes in the substance P immunoreactive axons occurred after removal of the superior cervical ganglion. It is concluded that the iris and the cornea are supplied by sensory nerves containing substance P immunoreactivity.

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JO - Neuroscience letters

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Substance P immunoreactive sensory nerves supply the rat iris and cornea

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