Substance P in nerve tissue in the gut.

M. Costa; J. B. Furness; R. Franco; I. Llewellyn-Smith; R. Murphy; A. M. Beardsley

Substance P in nerve tissue in the gut.

M. Costa, J. B. Furness, R. Franco, I. Llewellyn-Smith, R. Murphy, A. M. Beardsley

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

18 Citations (Scopus)

Abstract

Substance P is present in intrinsic nerves in the intestine and in some extrinsic sensory nerves. It can be released from these nerves to act on the muscle layers and on other enteric neurons. Immunohistochemical studies show that the enteric substance P neurons are short and branch profusely to supply all intestinal layers. Pharmacological studies indicate that enteric substance P neurons receive inputs from enteric cholinergic interneurons. This suggests that these neurons are part of multineuronal nerve pathways in the intestine. The substance P neurons are not essential for the enteric reflexes which subserve peristalsis but they appear to modulate these reflexes.

Original language	English
Title of host publication	Substance P in the Nervous System
Subtitle of host publication	Ciba Foundation Symposium 91
Pages	129-144
Number of pages	16
Publication status	Published - 1 Jan 1982

Publication series

Name	Ciba Foundation symposium
ISSN (Print)	0300-5208

Name	Novartis Foundation Symposia
Volume	91

Access to Document

Link to publication in Scopus

Fingerprint Dive into the research topics of 'Substance P in nerve tissue in the gut.'. Together they form a unique fingerprint.

Cite this

@inbook{23621567819446dba1d72d7a64a75113,

title = "Substance P in nerve tissue in the gut.",

abstract = "Substance P is present in intrinsic nerves in the intestine and in some extrinsic sensory nerves. It can be released from these nerves to act on the muscle layers and on other enteric neurons. Immunohistochemical studies show that the enteric substance P neurons are short and branch profusely to supply all intestinal layers. Pharmacological studies indicate that enteric substance P neurons receive inputs from enteric cholinergic interneurons. This suggests that these neurons are part of multineuronal nerve pathways in the intestine. The substance P neurons are not essential for the enteric reflexes which subserve peristalsis but they appear to modulate these reflexes.",

author = "M. Costa and Furness, {J. B.} and R. Franco and I. Llewellyn-Smith and R. Murphy and Beardsley, {A. M.}",

year = "1982",

month = jan,

day = "1",

language = "English",

isbn = "0272796557",

series = "Ciba Foundation symposium",

pages = "129--144",

booktitle = "Substance P in the Nervous System",

}

Substance P in nerve tissue in the gut. / Costa, M.; Furness, J. B.; Franco, R.; Llewellyn-Smith, I.; Murphy, R.; Beardsley, A. M.

Substance P in the Nervous System: Ciba Foundation Symposium 91. 1982. p. 129-144 (Ciba Foundation symposium), (Novartis Foundation Symposia; Vol. 91).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

TY - CHAP

T1 - Substance P in nerve tissue in the gut.

AU - Costa, M.

AU - Furness, J. B.

AU - Franco, R.

AU - Llewellyn-Smith, I.

AU - Murphy, R.

AU - Beardsley, A. M.

PY - 1982/1/1

Y1 - 1982/1/1

N2 - Substance P is present in intrinsic nerves in the intestine and in some extrinsic sensory nerves. It can be released from these nerves to act on the muscle layers and on other enteric neurons. Immunohistochemical studies show that the enteric substance P neurons are short and branch profusely to supply all intestinal layers. Pharmacological studies indicate that enteric substance P neurons receive inputs from enteric cholinergic interneurons. This suggests that these neurons are part of multineuronal nerve pathways in the intestine. The substance P neurons are not essential for the enteric reflexes which subserve peristalsis but they appear to modulate these reflexes.

AB - Substance P is present in intrinsic nerves in the intestine and in some extrinsic sensory nerves. It can be released from these nerves to act on the muscle layers and on other enteric neurons. Immunohistochemical studies show that the enteric substance P neurons are short and branch profusely to supply all intestinal layers. Pharmacological studies indicate that enteric substance P neurons receive inputs from enteric cholinergic interneurons. This suggests that these neurons are part of multineuronal nerve pathways in the intestine. The substance P neurons are not essential for the enteric reflexes which subserve peristalsis but they appear to modulate these reflexes.

UR - http://www.scopus.com/inward/record.url?scp=0020442935&partnerID=8YFLogxK

M3 - Chapter

C2 - 6183066

AN - SCOPUS:0020442935

SN - 0272796557

T3 - Ciba Foundation symposium

SP - 129

EP - 144

BT - Substance P in the Nervous System

ER -