Superior mesenteric artery first combined with uncinate process approach versus uncinate process first approach in pancreatoduodenectomy: a comparative study evaluating perioperative outcomes

Shailesh V. Shrikhande, Savio George Barreto, Yashodhan D. Bodhankar, Kunal Suradkar, Guruprasad Shetty, Rohini Hawaldar, Mahesh Goel, Parul J. Shukla

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

Purpose: During pancreatoduodenectomy (PD), two techniques have been described to dissect the head of pancreas, viz. the superior mesenteric artery (SMA) approach by dissecting the uncinate process and the uncinate process first approach. Methods: Forty-four consecutive patients, who underwent PD between June 2009 and April 2010, were analyzed. Thirty patients underwent the SMA first approach along with uncinate dissection (group 1), while 14 patients underwent the uncinate process first approach (group 2). Results: There were 30 male and 14 female patients. The median age was 51 years (range 19-76 years). Median intraoperative blood loss in group 1 was 800 ml, while that in group 2 was 600 ml. A mean of 0.52 units of blood were transfused in group 1 (range 0-3) compared to 0.2 units in group 2 (range 0-1). The median operative time in group 1 was 457.5 min and the median operative time was 450 min in group 2. Complication rate was 40% and 14.3% in groups 1 and 2, respectively. Median duration of hospital stay was 14 days in group 1 and 12.5 days in group 2. Median nodes resected in group 1 were 8 (range 0-26), while in group 2 they were 9 (range 2-14). Resection margins were positive in two cases (one in each group). There were two mortalities in group 1 and no mortalities in group 2. None of the above differences were significant. Conclusions: SMA first is a safe technique. It compares well with the uncinate first approach in terms of operative time, blood loss, number of lymph nodes retrieved, margin positivity and operative morbidity. Both techniques may be useful in situations such as a large uncinate process tumor or when superior mesenteric vein/portal vein/superior mesenteric artery involvement is suspected or present. Further studies, evaluating data related to specific predefined uncinate tumors, would be the next logical step in further defining the precise role of these techniques.

Original languageEnglish
Pages (from-to)1205-1212
Number of pages8
JournalLangenbeck's Archives of Surgery
Volume396
Issue number8
DOIs
Publication statusPublished - Dec 2011
Externally publishedYes

Keywords

  • Pancreatic cancer
  • Pancreatoduodenectomy
  • Perioperative outcomes
  • Resection margins
  • Results
  • Superior mesenteric artery

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