Suppressing regrowth of microfluidic generated drug nanocrystals using polyelectrolyte coatings

Selvi Dev, Jeremiah Toster, S Prasanna, Melinda Fitzgerald, K Iyer, Colin Raston

    Research output: Contribution to journalArticle

    14 Citations (Scopus)

    Abstract

    Crystalline meloxicam nanoparticles <100 nm in diameter are accessible using a microfluidic platform without the use of organic solvents, with a subsequent layer-by-layer polyelectrolyte encapsulation being effective in suppressing growth of macrocrystals, and imparting high colloidal stability for sustained release over 6-8 h with a t1/2ca.180 min.

    Original languageEnglish
    Pages (from-to)695-698
    Number of pages4
    JournalRSC Advances
    Volume3
    Issue number3
    DOIs
    Publication statusPublished - 21 Jan 2013

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