Allograft rejection is the major obstacle to successful corneal transplantation in high-risk cases. The risk factors are well recognized. Within the high-risk group, surgeons can influence graft survival by MHC antigen matching, by immunosuppression, by decreasing the number of antigen-presenting cells gaining access to the graft, and by avoiding up-regulation of MHC expression through the suppression of post-operative inflammation.
|Title of host publication||New Microsurgical Concepts II|
|Subtitle of host publication||Cornea, Posterior Segment, External Microsurgery|
|Editors||J Draeger, R Winter|
|Place of Publication||Basel|
|Number of pages||9|
|Publication status||Published - 1989|
|Name||Developments in ophthalmology|