Synthesis of myo-inositol 1,2,4,5-tetrakisphosphate, a Ca2+-mobilising tetrakisphosphate with a potency similar to myo-inositol 1,4,5-trisphosphate

Stephen J. Mills, Stephen T. Safrany, Robert A. Wilcox, Stefan R. Nahorski, Barry VL Potter

Research output: Contribution to journalArticlepeer-review

22 Citations (Scopus)

Abstract

The synthesis of myo-inositol 1,2,4,5-tetrakisphosphate from inositol is described; this tetrakisphosphate is a highly potent Ca2+-mobilising agonist at the Ins(1,4,5)P3 receptor.

Original languageEnglish
Pages (from-to)1505-1510
Number of pages6
JournalBioorganic and Medicinal Chemistry Letters
Volume3
Issue number8
DOIs
Publication statusPublished - Aug 1993
Externally publishedYes

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