Synthesis of myo-inositol 1,2,4,5-tetrakisphosphate, a Ca2+-mobilising tetrakisphosphate with a potency similar to myo-inositol 1,4,5-trisphosphate

Stephen J. Mills; Stephen T. Safrany; Robert A. Wilcox; Stefan R. Nahorski; Barry VL Potter

doi:10.1016/S0960-894X(00)80007-4

Synthesis of myo-inositol 1,2,4,5-tetrakisphosphate, a Ca²⁺-mobilising tetrakisphosphate with a potency similar to myo-inositol 1,4,5-trisphosphate

Stephen J. Mills, Stephen T. Safrany, Robert A. Wilcox, Stefan R. Nahorski, Barry VL Potter

Research output: Contribution to journal › Article › peer-review

23 Citations (Scopus)

Abstract

The synthesis of myo-inositol 1,2,4,5-tetrakisphosphate from inositol is described; this tetrakisphosphate is a highly potent Ca²⁺-mobilising agonist at the Ins(1,4,5)P₃ receptor.

Original language	English
Pages (from-to)	1505-1510
Number of pages	6
Journal	Bioorganic & Medicinal Chemistry Letters
Volume	3
Issue number	8
DOIs	https://doi.org/10.1016/S0960-894X(00)80007-4
Publication status	Published - Aug 1993
Externally published	Yes

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title = "Synthesis of myo-inositol 1,2,4,5-tetrakisphosphate, a Ca2+-mobilising tetrakisphosphate with a potency similar to myo-inositol 1,4,5-trisphosphate",

abstract = "The synthesis of myo-inositol 1,2,4,5-tetrakisphosphate from inositol is described; this tetrakisphosphate is a highly potent Ca2+-mobilising agonist at the Ins(1,4,5)P3 receptor.",

author = "Mills, {Stephen J.} and Safrany, {Stephen T.} and Wilcox, {Robert A.} and Nahorski, {Stefan R.} and Potter, {Barry VL}",

year = "1993",

month = aug,

doi = "10.1016/S0960-894X(00)80007-4",

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AU - Mills, Stephen J.

AU - Safrany, Stephen T.

AU - Wilcox, Robert A.

AU - Nahorski, Stefan R.

AU - Potter, Barry VL

PY - 1993/8

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AB - The synthesis of myo-inositol 1,2,4,5-tetrakisphosphate from inositol is described; this tetrakisphosphate is a highly potent Ca2+-mobilising agonist at the Ins(1,4,5)P3 receptor.

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DO - 10.1016/S0960-894X(00)80007-4

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JO - Bioorganic & Medicinal Chemistry Letters

JF - Bioorganic & Medicinal Chemistry Letters

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ER -

Synthesis of myo-inositol 1,2,4,5-tetrakisphosphate, a Ca²⁺-mobilising tetrakisphosphate with a potency similar to myo-inositol 1,4,5-trisphosphate

Abstract

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