Synthetic strategies for radioligands for in vivo imaging of brain cannabinoid type-1 receptors

Muneer Ahamed; Alfons Verbruggen; Guy Bormans

doi:10.1002/jlcr.3017

Synthetic strategies for radioligands for in vivo imaging of brain cannabinoid type-1 receptors

Muneer Ahamed, Alfons Verbruggen, Guy Bormans

Research output: Contribution to journal › Review article › peer-review

3 Citations (Scopus)

Abstract

Despite its abundant expression in the brain, the cannabinoid type-1 (CB1) receptor was discovered only in 1988. During the last decade, efforts from several research groups have made it possible to visualize the CB1 receptor in vivo to unravel its role in the brain physiology and pathology. This review discusses strategies for (radio)synthesis of radioligands for in vivo imaging of CB1 receptors.

Original language	English
Pages (from-to)	207-214
Number of pages	8
Journal	Journal of Labelled Compounds and Radiopharmaceuticals
Volume	56
Issue number	3-4
DOIs	https://doi.org/10.1002/jlcr.3017
Publication status	Published - Mar 2013

Keywords

CB1 receptors
in vivo imaging
positron emission tomography
radiosynthesis

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10.1002/jlcr.3017

Cite this

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abstract = "Despite its abundant expression in the brain, the cannabinoid type-1 (CB1) receptor was discovered only in 1988. During the last decade, efforts from several research groups have made it possible to visualize the CB1 receptor in vivo to unravel its role in the brain physiology and pathology. This review discusses strategies for (radio)synthesis of radioligands for in vivo imaging of CB1 receptors.",

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Synthetic strategies for radioligands for in vivo imaging of brain cannabinoid type-1 receptors

Abstract

Keywords

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