Despite its abundant expression in the brain, the cannabinoid type-1 (CB1) receptor was discovered only in 1988. During the last decade, efforts from several research groups have made it possible to visualize the CB1 receptor in vivo to unravel its role in the brain physiology and pathology. This review discusses strategies for (radio)synthesis of radioligands for in vivo imaging of CB1 receptors.
|Number of pages||8|
|Journal||Journal of Labelled Compounds and Radiopharmaceuticals|
|Publication status||Published - Mar 2013|
- CB1 receptors
- in vivo imaging
- positron emission tomography