TY - JOUR
T1 - Text message intervention delivered from Australian general practices to improve breast cancer survivors' physical activity and cardiovascular risk factors
T2 - protocol for the EMPOWER-SMS-GP effectiveness implementation randomised controlled trial
AU - Singleton, Anna C.
AU - Partridge, Stephanie R.
AU - Hyun, Karice K.
AU - Mitchell, Christine
AU - Raeside, Rebecca
AU - Hafiz, Nashid
AU - Nickel, Brooke
AU - Mizrahi, David
AU - Todd, Allyson Ruth
AU - McIntosh, Jennifer
AU - Chan, Raymond J.
AU - Stuart, Kirsty E.
AU - Ee, Carolyn
AU - Elder, Elisabeth
AU - Redfern, Julie
PY - 2024/12
Y1 - 2024/12
N2 - INTRODUCTION: Australian breast cancer survivors are at increased risk of cardiovascular disease and mortality, partly due to behavioural risk factors, including unhealthy diet and physical inactivity. Guidelines recommend health promotion delivered by general practitioners (GPs), but resources (ie, time and funding) are limited. Text message interventions sent from general practice to survivors may offer a low-resource solution but have not been evaluated. This randomised controlled trial (RCT) aims to evaluate the effectiveness and implementation of a text message intervention called EMPOWER-SMS-GP in Australian general practices. METHODS AND ANALYSIS: Multi-centre single-blind hybrid I RCT (n=678; 1:1 allocation) comparing EMPOWER-SMS-GP (n=339) to usual care (n=339) at 6 months (postintervention), 12, 18 and 24 months (maintenance) and parallel mixed-methods process evaluation using the Reach, Effectiveness, Adoption, Implementation and Maintenance framework. INCLUSION: adults (≥18 years old) with early-stage breast cancer, completed active treatment ≤3 years ago, have a mobile phone and attended ≥1 GP appointment within 24 months. PRIMARY OUTCOME: between-group difference in mean physical activity (metabolic equivalent minutes/day) at 6 months, measured using an accelerometer. Secondary outcomes include self-reported physical activity, diet, quality of life, financial or psychological distress, fear of cancer recurrence, endocrine therapy adherence and body mass index. Statistical analyses (intention-to-treat) will include t-test (primary outcome) and linear and logistic mixed-effects regression models. ETHICS AND DISSEMINATION: Approval received from the University of Sydney Human Research Ethics Committee (Number 2023/081). Trial results will be disseminated in peer-reviewed publications, presentations, lay summaries, videos and audio for scientific, government and public audiences.
AB - INTRODUCTION: Australian breast cancer survivors are at increased risk of cardiovascular disease and mortality, partly due to behavioural risk factors, including unhealthy diet and physical inactivity. Guidelines recommend health promotion delivered by general practitioners (GPs), but resources (ie, time and funding) are limited. Text message interventions sent from general practice to survivors may offer a low-resource solution but have not been evaluated. This randomised controlled trial (RCT) aims to evaluate the effectiveness and implementation of a text message intervention called EMPOWER-SMS-GP in Australian general practices. METHODS AND ANALYSIS: Multi-centre single-blind hybrid I RCT (n=678; 1:1 allocation) comparing EMPOWER-SMS-GP (n=339) to usual care (n=339) at 6 months (postintervention), 12, 18 and 24 months (maintenance) and parallel mixed-methods process evaluation using the Reach, Effectiveness, Adoption, Implementation and Maintenance framework. INCLUSION: adults (≥18 years old) with early-stage breast cancer, completed active treatment ≤3 years ago, have a mobile phone and attended ≥1 GP appointment within 24 months. PRIMARY OUTCOME: between-group difference in mean physical activity (metabolic equivalent minutes/day) at 6 months, measured using an accelerometer. Secondary outcomes include self-reported physical activity, diet, quality of life, financial or psychological distress, fear of cancer recurrence, endocrine therapy adherence and body mass index. Statistical analyses (intention-to-treat) will include t-test (primary outcome) and linear and logistic mixed-effects regression models. ETHICS AND DISSEMINATION: Approval received from the University of Sydney Human Research Ethics Committee (Number 2023/081). Trial results will be disseminated in peer-reviewed publications, presentations, lay summaries, videos and audio for scientific, government and public audiences.
KW - Cell Phone
KW - Health Services
KW - Implementation Science
KW - Oncology
KW - Primary Care
KW - Public Health
KW - breast cancer survivor
KW - physical activity
KW - cardiovascular risk factors
UR - http://www.scopus.com/inward/record.url?scp=85212459750&partnerID=8YFLogxK
UR - http://purl.org/au-research/grants/NHMRC/1194051
U2 - 10.1136/bmjopen-2024-090984
DO - 10.1136/bmjopen-2024-090984
M3 - Article
C2 - 39663171
AN - SCOPUS:85212459750
SN - 2044-6055
VL - 14
JO - BMJ Open
JF - BMJ Open
IS - 12
M1 - e090984
ER -