The chemistry of phthalide-3-carboxylic acid. VII. reaction with isoquinoline derivatives

Cosimo Donati, Tran V Hung, Rolf H Prager

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Phthalide-3-carboxylic acid has been decarboxylated in the presence of isoquinoline, 1-chloroisoquinoline and isoquinoline N-oxides to give low yields of compounds resulting from alkylation of the isoquinoline heterocycle at C1 with a phthalidyl group. Attempted Barton decarboxylation-alkylation in the presence of isoquinolinium salts was unsuccessful.

    Original languageEnglish
    Pages (from-to)375-381
    Number of pages7
    JournalAustralian Journal of Chemistry
    Volume43
    Issue number2
    DOIs
    Publication statusPublished - 1990

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