The Collaborative Ocular Tuberculosis Study (COTS) Consensus (CON) Group Meeting Proceedings

The Collaborative Ocular Tuberculosis Study Group, Justine R. Smith

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

An international, expert led consensus initiative was set up by the Collaborative Ocular Tuberculosis Study (COTS) group to develop systematic, evidence, and experience-based recommendations for the treatment of ocular TB using a modified Delphi technique process. In the first round of Delphi, the group identified clinical scenarios pertinent to ocular TB based on five clinical phenotypes (anterior uveitis, intermediate uveitis, choroiditis, retinal vasculitis, and panuveitis). Using an interactive online questionnaires, guided by background knowledge from published literature, 486 consensus statements for initiating ATT were generated and deliberated amongst 81 global uveitis experts. The median score of five was considered reaching consensus for initiating ATT. The median score of four was tabled for deliberation through Delphi round 2 in a face-to-face meeting. This report describes the methodology adopted and followed through the consensus process, which help elucidate the guidelines for initiating ATT in patients with choroidal TB.

Original languageEnglish
Pages (from-to)85-95
Number of pages11
JournalOcular Immunology and Inflammation
Volume28
Issue numbersup1
Early online date6 Apr 2020
DOIs
Publication statusPublished - 2020

Keywords

  • Antitubercular therapy
  • choroiditis
  • Collaborative Ocular Tuberculosis Study Consensus (COTS CON)
  • consensus guidelines
  • ocular tuberculosis

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