TY - JOUR
T1 - The diagnostic accuracy of cone-beam computed tomography for assessing in vitro osseous alterations of the mandibular condyle
T2 - a systematic review and meta-analysis
AU - Al Amin, Nur
AU - Farook, Taseef Hasan
AU - Oscandar, Fahmi
AU - Abdullah, Mohd Faizal
AU - Ibrahim, Norliza Binti
AU - Eusufzai, Sumaiya Zabin
AU - Abdullah, Johari Yap
PY - 2025/10
Y1 - 2025/10
N2 - Objective: To determine the diagnostic accuracy of cone-beam computed tomography (CBCT) in detecting simulated bony changes in the mandibular condyle by assessing the sensitivity and specificity. Methods: This review adhered to PRISMA guidelines. Following predefined eligibility criteria, a search was conducted in four electronic databases in June 2024. The study-level risk of bias was assessed using a diagnostic test accuracy checklist provided by the Joanna Briggs Institute. Pooled estimates of sensitivity and specificity were calculated using a bivariate random-effects model. Results: Among 1,803 potentially eligible references, six met the inclusion criteria for qualitative synthesis, and three for meta-analysis. The meta-analysis revealed that the index test, CBCT, had a low pooled sensitivity of 0.54 and a high specificity of 0.93 for detecting simulated defects of the mandibular condyle. Computed tomography exhibited a lower sensitivity of 0.37, but similar specificity of 0.93 like CBCT. Out of the six studies, five were found to have a low risk of bias. Conclusions: Cone-beam computed tomography is found to be more accurate than other modalities for detecting condylar bony changes, effectively ruling out false positives, but with a risk of missing true positives. A smaller field of view and voxel size may provide more accurate detection.
AB - Objective: To determine the diagnostic accuracy of cone-beam computed tomography (CBCT) in detecting simulated bony changes in the mandibular condyle by assessing the sensitivity and specificity. Methods: This review adhered to PRISMA guidelines. Following predefined eligibility criteria, a search was conducted in four electronic databases in June 2024. The study-level risk of bias was assessed using a diagnostic test accuracy checklist provided by the Joanna Briggs Institute. Pooled estimates of sensitivity and specificity were calculated using a bivariate random-effects model. Results: Among 1,803 potentially eligible references, six met the inclusion criteria for qualitative synthesis, and three for meta-analysis. The meta-analysis revealed that the index test, CBCT, had a low pooled sensitivity of 0.54 and a high specificity of 0.93 for detecting simulated defects of the mandibular condyle. Computed tomography exhibited a lower sensitivity of 0.37, but similar specificity of 0.93 like CBCT. Out of the six studies, five were found to have a low risk of bias. Conclusions: Cone-beam computed tomography is found to be more accurate than other modalities for detecting condylar bony changes, effectively ruling out false positives, but with a risk of missing true positives. A smaller field of view and voxel size may provide more accurate detection.
KW - Degenerative diseases
KW - Diagnostic accuracy test
KW - Temporomandibular disorders
KW - Temporomandibular joint
UR - http://www.scopus.com/inward/record.url?scp=105003951111&partnerID=8YFLogxK
U2 - 10.1007/s11282-025-00821-6
DO - 10.1007/s11282-025-00821-6
M3 - Review article
AN - SCOPUS:105003951111
SN - 0911-6028
VL - 41
SP - 449
EP - 459
JO - Oral Radiology
JF - Oral Radiology
IS - 4
ER -