The effect of learning on ventilatory responses to inspiratory threshold loading in COPD

Gavin A. Sturdy; David R. Hillman; Daniel J. Green; Sue C. Jenkins; Nola M. Cecins; Peter R. Eastwood

doi:10.1016/j.rmed.2003.07.005

The effect of learning on ventilatory responses to inspiratory threshold loading in COPD

Gavin A. Sturdy, David R. Hillman, Daniel J. Green, Sue C. Jenkins, Nola M. Cecins, Peter R. Eastwood

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

Background: Progressive threshold loading (PTL) is a common test of respiratory muscle endurance. Healthy naïve subjects improve endurance with successive exposures to PTL by altering their breathing responses, thus necessitating a familiarization period before reproducible measures can be obtained. This study sought to determine whether a similar "learning effect" is evident in patients with COPD, and what the mechanism of any such effect may be. Methods: Ten subjects with COPD (FEV₁ 34±13% predicted underwent PTL on four occasions (>24h apart). During PTL measurements were obtained of breathing pattern and maximum threshold pressure (P_thmax) achieved. Maximum inspiratory pressure (P_Imax) was measured on each occasion. Results: Over the four tests P_Imax improved by 21±16% (SD) (P<0.05) and P_thmax by 32±21% (P<0.05) with a plateau in these measures achieved by test three. P_thmax/ P_Imax was unchanged, being 61±11% at test one and 67±12% at test four. In contrast to healthy subjects, PTL was not associated with increased expiratory time or decreased end-expiratory lung volume. Conclusions: In contrast to P_Imax and P_thmax, which changed with successive tests, a single measure of the ratio P_thmax/P_Imax may present a useful guide to the endurance capacity of the respiratory muscles in patients with COPD.

Original language	English
Pages (from-to)	1-8
Number of pages	8
Journal	Respiratory Medicine
Volume	98
Issue number	1
DOIs	https://doi.org/10.1016/j.rmed.2003.07.005
Publication status	Published - 1 Jan 2004
Externally published	Yes

Bibliographical note

Funding Information:
This work was funded in part by National Health and Medical Research Council (Australia) Grant 212016.

Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.

Keywords

Inspiratory muscles
Respiratory muscle endurance
Respiratory muscle strength

Access to Document

10.1016/j.rmed.2003.07.005Licence: In Copyright

Fingerprint Dive into the research topics of 'The effect of learning on ventilatory responses to inspiratory threshold loading in COPD'. Together they form a unique fingerprint.

Cite this

@article{de1cfa06a4954becbdd7ce8de831dafc,

title = "The effect of learning on ventilatory responses to inspiratory threshold loading in COPD",

abstract = "Background: Progressive threshold loading (PTL) is a common test of respiratory muscle endurance. Healthy na{\"i}ve subjects improve endurance with successive exposures to PTL by altering their breathing responses, thus necessitating a familiarization period before reproducible measures can be obtained. This study sought to determine whether a similar {"}learning effect{"} is evident in patients with COPD, and what the mechanism of any such effect may be. Methods: Ten subjects with COPD (FEV1 34±13% predicted underwent PTL on four occasions (>24h apart). During PTL measurements were obtained of breathing pattern and maximum threshold pressure (Pthmax) achieved. Maximum inspiratory pressure (PImax) was measured on each occasion. Results: Over the four tests PImax improved by 21±16% (SD) (P<0.05) and Pthmax by 32±21% (P<0.05) with a plateau in these measures achieved by test three. Pthmax/ PImax was unchanged, being 61±11% at test one and 67±12% at test four. In contrast to healthy subjects, PTL was not associated with increased expiratory time or decreased end-expiratory lung volume. Conclusions: In contrast to PImax and Pthmax, which changed with successive tests, a single measure of the ratio Pthmax/PImax may present a useful guide to the endurance capacity of the respiratory muscles in patients with COPD.",

keywords = "Inspiratory muscles, Respiratory muscle endurance, Respiratory muscle strength",

author = "Sturdy, {Gavin A.} and Hillman, {David R.} and Green, {Daniel J.} and Jenkins, {Sue C.} and Cecins, {Nola M.} and Eastwood, {Peter R.}",

year = "2004",

month = jan,

day = "1",

doi = "10.1016/j.rmed.2003.07.005",

language = "English",

volume = "98",

pages = "1--8",

journal = "Respiratory Medicine",

issn = "0954-6111",

publisher = "Elsievier Science",

number = "1",

}

TY - JOUR

T1 - The effect of learning on ventilatory responses to inspiratory threshold loading in COPD

AU - Sturdy, Gavin A.

AU - Hillman, David R.

AU - Green, Daniel J.

AU - Jenkins, Sue C.

AU - Cecins, Nola M.

AU - Eastwood, Peter R.

PY - 2004/1/1

Y1 - 2004/1/1

N2 - Background: Progressive threshold loading (PTL) is a common test of respiratory muscle endurance. Healthy naïve subjects improve endurance with successive exposures to PTL by altering their breathing responses, thus necessitating a familiarization period before reproducible measures can be obtained. This study sought to determine whether a similar "learning effect" is evident in patients with COPD, and what the mechanism of any such effect may be. Methods: Ten subjects with COPD (FEV1 34±13% predicted underwent PTL on four occasions (>24h apart). During PTL measurements were obtained of breathing pattern and maximum threshold pressure (Pthmax) achieved. Maximum inspiratory pressure (PImax) was measured on each occasion. Results: Over the four tests PImax improved by 21±16% (SD) (P<0.05) and Pthmax by 32±21% (P<0.05) with a plateau in these measures achieved by test three. Pthmax/ PImax was unchanged, being 61±11% at test one and 67±12% at test four. In contrast to healthy subjects, PTL was not associated with increased expiratory time or decreased end-expiratory lung volume. Conclusions: In contrast to PImax and Pthmax, which changed with successive tests, a single measure of the ratio Pthmax/PImax may present a useful guide to the endurance capacity of the respiratory muscles in patients with COPD.

AB - Background: Progressive threshold loading (PTL) is a common test of respiratory muscle endurance. Healthy naïve subjects improve endurance with successive exposures to PTL by altering their breathing responses, thus necessitating a familiarization period before reproducible measures can be obtained. This study sought to determine whether a similar "learning effect" is evident in patients with COPD, and what the mechanism of any such effect may be. Methods: Ten subjects with COPD (FEV1 34±13% predicted underwent PTL on four occasions (>24h apart). During PTL measurements were obtained of breathing pattern and maximum threshold pressure (Pthmax) achieved. Maximum inspiratory pressure (PImax) was measured on each occasion. Results: Over the four tests PImax improved by 21±16% (SD) (P<0.05) and Pthmax by 32±21% (P<0.05) with a plateau in these measures achieved by test three. Pthmax/ PImax was unchanged, being 61±11% at test one and 67±12% at test four. In contrast to healthy subjects, PTL was not associated with increased expiratory time or decreased end-expiratory lung volume. Conclusions: In contrast to PImax and Pthmax, which changed with successive tests, a single measure of the ratio Pthmax/PImax may present a useful guide to the endurance capacity of the respiratory muscles in patients with COPD.

KW - Inspiratory muscles

KW - Respiratory muscle endurance

KW - Respiratory muscle strength

UR - http://www.scopus.com/inward/record.url?scp=0346505470&partnerID=8YFLogxK

U2 - 10.1016/j.rmed.2003.07.005

DO - 10.1016/j.rmed.2003.07.005

M3 - Article

C2 - 14959807

AN - SCOPUS:0346505470

VL - 98

SP - 1

EP - 8

JO - Respiratory Medicine

JF - Respiratory Medicine

SN - 0954-6111

IS - 1

ER -

The effect of learning on ventilatory responses to inspiratory threshold loading in COPD

Abstract

Bibliographical note

Keywords

Access to Document

Other files and links

Cite this