TY - JOUR
T1 - The effect of varying the number of contributors in the prosecution and alternate propositions
AU - Buckleton, John S.
AU - Bright, Jo Anne
AU - Cheng, Kevin
AU - Kelly, Hannah
AU - Taylor, Duncan A.
PY - 2019/1
Y1 - 2019/1
N2 - Using a simplified model, we examine the effect of varying the number of contributors in the prosecution and alternate propositions for a number of simulated examples. We compare the Slooten and Caliebe [1] solution, with several existing practices. Our own experience is that most laboratories, and ourselves, assign the number of contributors, N = n, by allele count and a manual examination of peak heights. The LRn for one or a very few values is calculated and typically one of these is presented, usually the most conservative. This gives an acceptable approximation. Reassessing the number of contributors if LR = 0 and adding one to N under both Hp and Ha to “fit” the POI may lead to a substantial overstatement of the LR. A more reasonable option is to allow optimisation of the assignment under Hp and Ha separately. We show that an additional contributor explained the single locus profile better when PHR≥0.51. This is pleasingly in line with current interpretation approaches. Collectively these trials, and the solid theoretical development, suggest that the Slooten and Caliebe approach preforms well.
AB - Using a simplified model, we examine the effect of varying the number of contributors in the prosecution and alternate propositions for a number of simulated examples. We compare the Slooten and Caliebe [1] solution, with several existing practices. Our own experience is that most laboratories, and ourselves, assign the number of contributors, N = n, by allele count and a manual examination of peak heights. The LRn for one or a very few values is calculated and typically one of these is presented, usually the most conservative. This gives an acceptable approximation. Reassessing the number of contributors if LR = 0 and adding one to N under both Hp and Ha to “fit” the POI may lead to a substantial overstatement of the LR. A more reasonable option is to allow optimisation of the assignment under Hp and Ha separately. We show that an additional contributor explained the single locus profile better when PHR≥0.51. This is pleasingly in line with current interpretation approaches. Collectively these trials, and the solid theoretical development, suggest that the Slooten and Caliebe approach preforms well.
KW - DNA mixture interpretation
KW - Number of contributors
KW - Slooten and Caliebe
UR - http://www.scopus.com/inward/record.url?scp=85056703398&partnerID=8YFLogxK
U2 - 10.1016/j.fsigen.2018.11.011
DO - 10.1016/j.fsigen.2018.11.011
M3 - Article
C2 - 30466054
AN - SCOPUS:85056703398
SN - 1872-4973
VL - 38
SP - 225
EP - 231
JO - Forensic Science International: Genetics
JF - Forensic Science International: Genetics
ER -