The human leucocyte P30 antigen: properties and assessment of value as a clonal marker

H. Zola, H. A. Moore, I. K. Hunter, A. Hohmann, P. J. Mcnamara, J. Bradley, P. Mum, A. Morley, J. V. Melo, D. Catovsky

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

FMC3 and FMC29 are monoclonal antibodies which react with a 30,000 Dalton molecule expressed on the lymphocyte surface membrane. The molecule is a protein which does not appear to be N‐glycosylated. The antigen, which is also expressed intracellularly, does not appear to be a marker of differentiation or maturation. Polyclonal cell populations, such as peripheral blood lymphocytes, show a bimodal distribution of surface antigen density, whilst monoclonal cell populations analysed quantitatively showed unimodal antigen density distributions. This suggests the antigen may be a clonal marker.

Original languageEnglish
Pages (from-to)60-70
Number of pages11
JournalTissue Antigens
Volume26
Issue number1
DOIs
Publication statusPublished - Jul 1985
Externally publishedYes

Fingerprint Dive into the research topics of 'The human leucocyte P30 antigen: properties and assessment of value as a clonal marker'. Together they form a unique fingerprint.

Cite this