Abstract
Introduction: Parkinson's disease (PD) poses significant challenges in managing symptoms, with medication adherence playing a crucial role in treatment efficacy. Understanding the impact of neurocognitive functioning and gender differences on medication adherence is essential for optimizing treatment outcomes in PD.
Objective: This study aimed to investigate the relationship between neurocognitive functioning, medication adherence, and gender differences in individuals with PD.
Methods: A sample of 120 individuals diagnosed with PD was recruited, and their medication adherence and neurocognitive functioning were assessed using validated measures. Statistical analyses, including correlational analyses and independent samples t-tests, were conducted to examine associations and gender differences.
Results: The findings revealed a significant gender disparity in medication adherence, with male participants demonstrating higher adherence levels than female participants. While a weak positive correlation was observed between neurocognitive functioning and medication adherence, it did not reach statistical significance.
Conclusion: The study highlights the complex interplay between neurocognitive functioning, medication adherence, and gender differences in individuals with PD. Tailored interventions addressing cognitive impairments and gender-specific factors are crucial for enhancing medication adherence and optimizing treatment outcomes in PD. Further research exploring longitudinal associations and other relevant factors is warranted to develop comprehensive interventions for individuals managing PD effectively.
Objective: This study aimed to investigate the relationship between neurocognitive functioning, medication adherence, and gender differences in individuals with PD.
Methods: A sample of 120 individuals diagnosed with PD was recruited, and their medication adherence and neurocognitive functioning were assessed using validated measures. Statistical analyses, including correlational analyses and independent samples t-tests, were conducted to examine associations and gender differences.
Results: The findings revealed a significant gender disparity in medication adherence, with male participants demonstrating higher adherence levels than female participants. While a weak positive correlation was observed between neurocognitive functioning and medication adherence, it did not reach statistical significance.
Conclusion: The study highlights the complex interplay between neurocognitive functioning, medication adherence, and gender differences in individuals with PD. Tailored interventions addressing cognitive impairments and gender-specific factors are crucial for enhancing medication adherence and optimizing treatment outcomes in PD. Further research exploring longitudinal associations and other relevant factors is warranted to develop comprehensive interventions for individuals managing PD effectively.
| Original language | English |
|---|---|
| Pages (from-to) | 2494-2503 |
| Number of pages | 10 |
| Journal | Journal of Population Therapeutics and Clinical Pharmacology, |
| Volume | 31 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2 Feb 2024 |
| Externally published | Yes |
Keywords
- Parkinson's disease
- medication adherence
- neurocognitive functioning
- gender differences
- treatment outcomes