The initiation site for recombination cog is at the 3′ end of the his-3 gene in Neurospora crassa

Frederick J. Bowring, David E.A. Catcheside

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    16 Citations (Scopus)

    Abstract

    Recombination at his-3 in Neurospora crassa is thought to be initiated through a site designated cog which lies in the his-3 to ad-3 interval of linkage group I. Fragments of the his-3 gene were used to transform various his-3 mutant alleles to prototrophy in order to link the genetic map to the nucleotide sequence. It was established that cog is at the 3′ end of his-3 and is therefore not the his-3 promoter. This suggests that cog may be dissimilar to a number of yeast recombinators which are associated with promoters of transcription.

    Original languageEnglish
    Pages (from-to)273-277
    Number of pages5
    JournalMGG Molecular & General Genetics
    Volume229
    Issue number2
    DOIs
    Publication statusPublished - Oct 1991

    Keywords

    • cog
    • Meiosis
    • Neurospora crassa
    • rec-2
    • Recombination

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