The optogenetic promise for oncology: Episode I

Alvaro Ingles-Prieto, Eva Reichhart, Karin Schelch, Harald Janovjak, Michael Grusch

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

As light-based control of fundamental signaling pathways is becoming a reality, the field of optogenetics is rapidly moving beyond neuroscience. We have recently developed receptor tyrosine kinases that are activated by light and control cell proliferation, epithelial–mesenchymal transition, and angiogenic sprouting—cell behaviors central to cancer progression.

Original languageEnglish
Article numbere964045
Number of pages4
JournalMolecular and Cellular Oncology
Volume1
Issue number4
DOIs
Publication statusPublished - 2014
Externally publishedYes

Keywords

  • hallmarks of cancer
  • Optogenetics
  • receptor tyrosine kinase
  • spatio-temporal control
  • synthetic physiology

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