1. The amounts by which various weights distended isolated segments from the distal colons of guinea‐pigs were measured. 2. Tetrodotoxin substantially reduced the distensibility of the intestine, but bretylium, guanethidine, hyoscine and methysergide had no significant effect. 3. It is concluded that a local reflex involving enteric inhibitory nerves causes an accommodation of the intestine to stretch.
|Number of pages||5|
|Journal||Clinical and Experimental Pharmacology and Physiology|
|Publication status||Published - Feb 1977|
- autonomic nervous system
- enteric reflexes
- intestinal motility