The prevalence and characteristics of obstructive sleep apnea in hospitalized patients with type 2 diabetes in China.

Puhong Zhang, Rui Zhang, Fang Zhao, Emma Heeley, Ching Chai-Coetzer, Jing Liu, Bo Feng, Ping Han, Qifu Li, Liao Sun, Yufeng Li, Shengying Dong, Xiaozhen Jiang, Chunhua Zhang, Jinhui Lu, Xingduan Guo, Lixin Guo, Ronald McEvoy, Linong Ji

    Research output: Contribution to journalArticle

    26 Citations (Scopus)

    Abstract

    Data on the prevalence of obstructive sleep apnea in subjects with type 2 diabetes mellitus in China is scarce. We conducted a multi-centre, cross-sectional study involving 12 hospitals from six regional cities to investigate the prevalence of obstructive sleep apnea in hospitalized patients with type 2 diabetes mellitus and to explore the association between obstructive sleep apnea and related risk factors, diabetic complications and comorbidities in China. Each hospital recruited at least 70 consecutive patients with type 2 diabetes mellitus who were admitted to the endocrinology ward. A total of 880 participants were enrolled and administered overnight sleep monitoring with a portable monitor (ApneaLink , ResMed, San Diego, CA, USA); other information was collected from medical charts and a standardized questionnaire. In this study, 60.0% (95% confidence interval: 56.8%, 63.2%) of hospitalized patients in China with type 2 diabetes mellitus had comorbid obstructive sleep apnea (apnea-hypopnea index ≥ 5). Only 1.5% (eight of 528) of the patients with both conditions had been diagnosed previously with obstructive sleep apnea. The prevalence of moderate-severe (apnea-hypopnea index ≥ 15) and severe obstructive sleep apnea (apnea-hypopnea index ≥ 30) was estimated to be 25.6% (22.7, 28.5%) and 10.3% (8.3, 12.4%), respectively. Age, sex, body mass index, snoring, reported breath-holding in sleep or gasping or choking arousal, sleepiness, diabetes duration, hypertension, diabetic nephropathy and cardiovascular diseases history were correlated significantly with the severity of obstructive sleep apnea. In China, the prevalence of obstructive sleep apnea in hospitalized patients with type 2 diabetes mellitus is high. Routine screening for and treatment of obstructive sleep apnea is an important, but often neglected, part of the management of diabetes.

    Original languageEnglish
    Pages (from-to)39-46
    Number of pages8
    JournalJournal of Sleep Research
    Volume25
    Issue number1
    DOIs
    Publication statusPublished - 1 Feb 2016

    Keywords

    • Continuous positive airway pressure
    • Percentage

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  • Cite this

    Zhang, P., Zhang, R., Zhao, F., Heeley, E., Chai-Coetzer, C., Liu, J., Feng, B., Han, P., Li, Q., Sun, L., Li, Y., Dong, S., Jiang, X., Zhang, C., Lu, J., Guo, X., Guo, L., McEvoy, R., & Ji, L. (2016). The prevalence and characteristics of obstructive sleep apnea in hospitalized patients with type 2 diabetes in China. Journal of Sleep Research, 25(1), 39-46. https://doi.org/10.1111/jsr.12334