TY - JOUR
T1 - The relationship between exercise dose and health-related quality of life with a phase III cardiac rehabilitation program
AU - Del Pozo-Cruz, Borja
AU - Carrick-Ranson, Graeme
AU - Reading, Stacey
AU - Nolan, Paul
AU - Dalleck, Lance
PY - 2018/4/1
Y1 - 2018/4/1
N2 - Purpose: To quantify the relationship between the change in exercise dose and health-related quality of life (HRQoL) in a cohort of patients participating in a community-based phase-3 cardiac rehabilitation (CR) program. Methods: A retrospective, pre-experimental (no control group) design of 58 participants that completed a phase-3, 12-week exercise-based CR program was used to test the current hypothesis. Self-reported HRQoL (36-Item Short Form Health Survey Version 2, SF-36v2) was assessed prior and after completing the CR program. The change in exercise dose was estimated from the assigned training load in weeks 1 and 12 of the CR program. A series of regression models were fitted to ascertain the relationship between the change in exercise dose and changes in the SF-36v2. Results: There was a strong quadratic trend between the change in exercise dose and the mean change in SF-36 Mental and Physical Health Summary Scores. Analysis of covariance showed that the mean changes in the SF-36 Summary Scores statistically fluctuate across quartiles of exercise dose. The data show that there is a threshold amount of increase in exercise (Q2; 350–510 kcal week− 1) needed to HRQoL and that greater amounts of exercise dose (Q3; 511–687 and Q4 ≥ 688 kcal week− 1) did not improve HRQoL further. Conclusions: The current findings suggest that physical and mental health-related quality of life are improved with a phase-3 CR program. The dose–response relationship observed indicates that a threshold exercise dose is required to improve HRQoL, and that larger doses of exercise do not confer further improvements in HRQoL.
AB - Purpose: To quantify the relationship between the change in exercise dose and health-related quality of life (HRQoL) in a cohort of patients participating in a community-based phase-3 cardiac rehabilitation (CR) program. Methods: A retrospective, pre-experimental (no control group) design of 58 participants that completed a phase-3, 12-week exercise-based CR program was used to test the current hypothesis. Self-reported HRQoL (36-Item Short Form Health Survey Version 2, SF-36v2) was assessed prior and after completing the CR program. The change in exercise dose was estimated from the assigned training load in weeks 1 and 12 of the CR program. A series of regression models were fitted to ascertain the relationship between the change in exercise dose and changes in the SF-36v2. Results: There was a strong quadratic trend between the change in exercise dose and the mean change in SF-36 Mental and Physical Health Summary Scores. Analysis of covariance showed that the mean changes in the SF-36 Summary Scores statistically fluctuate across quartiles of exercise dose. The data show that there is a threshold amount of increase in exercise (Q2; 350–510 kcal week− 1) needed to HRQoL and that greater amounts of exercise dose (Q3; 511–687 and Q4 ≥ 688 kcal week− 1) did not improve HRQoL further. Conclusions: The current findings suggest that physical and mental health-related quality of life are improved with a phase-3 CR program. The dose–response relationship observed indicates that a threshold exercise dose is required to improve HRQoL, and that larger doses of exercise do not confer further improvements in HRQoL.
KW - Cardiac rehabilitation
KW - Dose–response
KW - Energy expenditure
KW - Health-related quality of life
UR - http://www.scopus.com/inward/record.url?scp=85040657851&partnerID=8YFLogxK
U2 - 10.1007/s11136-018-1784-9
DO - 10.1007/s11136-018-1784-9
M3 - Article
SN - 0962-9343
VL - 27
SP - 993
EP - 998
JO - Quality of Life Research
JF - Quality of Life Research
IS - 4
ER -