The upper airway is most collapsible during expiration in obstructive sleep apnoea

A Osman; J Butler; S Gandevia; D Eckert

doi:10.1111/jsr.19_12765

Abstract

Upper airway collapsibility is an important contributor to obstructive sleep apnoea (OSA) pathogenesis. Pharyngeal dilator muscle activity varies throughout the respiratory cycle and may contribute to dynamic changes in upper airway collapsibility. We have recently shown that a test of upper airway collapsibility when
awake correlates (r = 0.8, n = 34) with upper airway collapsibility during sleep (Pcrit) in people with OSA. However, whether upper airway collapsibility varies throughout the respiratory cycle is unknown. Thus, this study aimed to quantify differences in pharyngeal muscle activity and upper airway collapsibility during different phases of the respiratory cycle.

Original language	English
Article number	O020
Pages (from-to)	9-10
Number of pages	2
Journal	Journal of Sleep Research
Volume	27
Issue number	S2
DOIs	https://doi.org/10.1111/jsr.19_12765
Publication status	Published - Oct 2018
Externally published	Yes
Event	Sleep Down Under 2018: 30th ASM of Australasian Sleep Association and the Australasian Sleep Technologists Association - Brisbane, Australia Duration: 17 Oct 2018 → 20 Oct 2018

Keywords

obstructive sleep apnoea
expiration
collapsible
upper airway

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title = "The upper airway is most collapsible during expiration in obstructive sleep apnoea",

abstract = "Upper airway collapsibility is an important contributor to obstructive sleep apnoea (OSA) pathogenesis. Pharyngeal dilator muscle activity varies throughout the respiratory cycle and may contribute to dynamic changes in upper airway collapsibility. We have recently shown that a test of upper airway collapsibility whenawake correlates (r = 0.8, n = 34) with upper airway collapsibility during sleep (Pcrit) in people with OSA. However, whether upper airway collapsibility varies throughout the respiratory cycle is unknown. Thus, this study aimed to quantify differences in pharyngeal muscle activity and upper airway collapsibility during different phases of the respiratory cycle.",

keywords = "obstructive sleep apnoea, expiration, collapsible, upper airway",

author = "A Osman and J Butler and S Gandevia and D Eckert",

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doi = "10.1111/jsr.19_12765",

language = "English",

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TY - JOUR

T1 - The upper airway is most collapsible during expiration in obstructive sleep apnoea

AU - Osman, A

AU - Butler, J

AU - Gandevia, S

AU - Eckert, D

PY - 2018/10

Y1 - 2018/10

N2 - Upper airway collapsibility is an important contributor to obstructive sleep apnoea (OSA) pathogenesis. Pharyngeal dilator muscle activity varies throughout the respiratory cycle and may contribute to dynamic changes in upper airway collapsibility. We have recently shown that a test of upper airway collapsibility whenawake correlates (r = 0.8, n = 34) with upper airway collapsibility during sleep (Pcrit) in people with OSA. However, whether upper airway collapsibility varies throughout the respiratory cycle is unknown. Thus, this study aimed to quantify differences in pharyngeal muscle activity and upper airway collapsibility during different phases of the respiratory cycle.

AB - Upper airway collapsibility is an important contributor to obstructive sleep apnoea (OSA) pathogenesis. Pharyngeal dilator muscle activity varies throughout the respiratory cycle and may contribute to dynamic changes in upper airway collapsibility. We have recently shown that a test of upper airway collapsibility whenawake correlates (r = 0.8, n = 34) with upper airway collapsibility during sleep (Pcrit) in people with OSA. However, whether upper airway collapsibility varies throughout the respiratory cycle is unknown. Thus, this study aimed to quantify differences in pharyngeal muscle activity and upper airway collapsibility during different phases of the respiratory cycle.

KW - obstructive sleep apnoea

KW - expiration

KW - collapsible

KW - upper airway

U2 - 10.1111/jsr.19_12765

DO - 10.1111/jsr.19_12765

M3 - Meeting Abstract

SN - 0962-1105

VL - 27

SP - 9

EP - 10

JO - Journal of Sleep Research

JF - Journal of Sleep Research

IS - S2

M1 - O020

T2 - Sleep Down Under 2018

Y2 - 17 October 2018 through 20 October 2018

ER -

The upper airway is most collapsible during expiration in obstructive sleep apnoea

Abstract

Keywords

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