The use of acyclovir in suspected encephalitis

J. Gleadle; C. Dixon; M. M. Brown; F. Schon

The use of acyclovir in suspected encephalitis

J. Gleadle, C. Dixon, M. M. Brown, F. Schon

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

The early use of intravenous acyclovir in herpes simplex encephalitis (HSE) is essential. However, rapid diagnostic tests are not freely available. Hence, all patients with suspected encephalitis may need to be commenced on acyclovir. In our study, of 34 patients with suspected encephalitis, only two eventually had HSE confirmed, 19 had encephalitis not due to herpes simplex and in 13 a non-encephalitic illness was finally diagnosed. Guidelines for the use of acyclovir in suspected encephalitis are given aimed at minimizing the drug cost whilst still protecting all cases of presumed HSE.

Original language	English
Pages (from-to)	7-8
Number of pages	2
Journal	Journal of the Royal Society of Medicine
Volume	87
Issue number	1
Publication status	Published - Jan 1994
Externally published	Yes

Keywords

acyclovir
encephalitis

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abstract = "The early use of intravenous acyclovir in herpes simplex encephalitis (HSE) is essential. However, rapid diagnostic tests are not freely available. Hence, all patients with suspected encephalitis may need to be commenced on acyclovir. In our study, of 34 patients with suspected encephalitis, only two eventually had HSE confirmed, 19 had encephalitis not due to herpes simplex and in 13 a non-encephalitic illness was finally diagnosed. Guidelines for the use of acyclovir in suspected encephalitis are given aimed at minimizing the drug cost whilst still protecting all cases of presumed HSE.",

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AB - The early use of intravenous acyclovir in herpes simplex encephalitis (HSE) is essential. However, rapid diagnostic tests are not freely available. Hence, all patients with suspected encephalitis may need to be commenced on acyclovir. In our study, of 34 patients with suspected encephalitis, only two eventually had HSE confirmed, 19 had encephalitis not due to herpes simplex and in 13 a non-encephalitic illness was finally diagnosed. Guidelines for the use of acyclovir in suspected encephalitis are given aimed at minimizing the drug cost whilst still protecting all cases of presumed HSE.

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The use of acyclovir in suspected encephalitis

Abstract

Keywords

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