THERE ARE FEW CATECHOLAMINE‐ OR NEUROPEPTIDE Y‐CONTAINING SYNAPSES IN THE INTERMEDIOLATERAL CELL COLUMN OF RAT THORACIC SPINAL CORD

Ida J. Llewellyn‐Smith; Jane B. Minson; Paul M. Pilowsky; John P. Chalmers

doi:10.1111/j.1440-1681.1991.tb01418.x

THERE ARE FEW CATECHOLAMINE‐ OR NEUROPEPTIDE Y‐CONTAINING SYNAPSES IN THE INTERMEDIOLATERAL CELL COLUMN OF RAT THORACIC SPINAL CORD

Ida J. Llewellyn‐Smith, Jane B. Minson, Paul M. Pilowsky, John P. Chalmers

Research output: Contribution to journal › Article › peer-review

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Abstract

1. A quantitative electron microscopic immunocytochemical technique was used to assess the number of synapses immunoreactive for tyrosine hydroxylase (TH), phenylethanolamine N‐methyltransferase (PNMT) and neuropeptide Y (NPY) in the intermediolateral cell column in segments T2 and T3 of rat thoracic spinal cord. 2. TH synapses comprised about 5%; PNMT synapses 1–2%; and NPY synapses 1–2% of the total number of synapses in the intermediolateral cell column. All three types of synapses were predominantly or exclusively on dendrites. 3. Our results suggest that catecholamine/NPY neurons may not provide a major synaptic input to sympathetic preganglionic neurons in rat upper thoracic spinal cord.

Original language	English
Pages (from-to)	111-115
Number of pages	5
Journal	Clinical and Experimental Pharmacology and Physiology
Volume	18
Issue number	2
DOIs	https://doi.org/10.1111/j.1440-1681.1991.tb01418.x
Publication status	Published - Feb 1991

Keywords

immunocytochemistry
neuropeptide Y
phenylethanolamine N‐methyltransferase
sympathetic preganglionic neurons
tyrosine hydroxylase
ultrastructure.

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title = "THERE ARE FEW CATECHOLAMINE‐ OR NEUROPEPTIDE Y‐CONTAINING SYNAPSES IN THE INTERMEDIOLATERAL CELL COLUMN OF RAT THORACIC SPINAL CORD",

abstract = "1. A quantitative electron microscopic immunocytochemical technique was used to assess the number of synapses immunoreactive for tyrosine hydroxylase (TH), phenylethanolamine N‐methyltransferase (PNMT) and neuropeptide Y (NPY) in the intermediolateral cell column in segments T2 and T3 of rat thoracic spinal cord. 2. TH synapses comprised about 5%; PNMT synapses 1–2%; and NPY synapses 1–2% of the total number of synapses in the intermediolateral cell column. All three types of synapses were predominantly or exclusively on dendrites. 3. Our results suggest that catecholamine/NPY neurons may not provide a major synaptic input to sympathetic preganglionic neurons in rat upper thoracic spinal cord.",

keywords = "immunocytochemistry, neuropeptide Y, phenylethanolamine N‐methyltransferase, sympathetic preganglionic neurons, tyrosine hydroxylase, ultrastructure.",

author = "Llewellyn‐Smith, {Ida J.} and Minson, {Jane B.} and Pilowsky, {Paul M.} and Chalmers, {John P.}",

year = "1991",

month = feb,

doi = "10.1111/j.1440-1681.1991.tb01418.x",

language = "English",

volume = "18",

pages = "111--115",

journal = "Clinical and Experimental Pharmacology and Physiology",

issn = "0305-1870",

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number = "2",

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THERE ARE FEW CATECHOLAMINE‐ OR NEUROPEPTIDE Y‐CONTAINING SYNAPSES IN THE INTERMEDIOLATERAL CELL COLUMN OF RAT THORACIC SPINAL CORD. / Llewellyn‐Smith, Ida J.; Minson, Jane B.; Pilowsky, Paul M. et al.
In: Clinical and Experimental Pharmacology and Physiology, Vol. 18, No. 2, 02.1991, p. 111-115.

Research output: Contribution to journal › Article › peer-review

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AU - Llewellyn‐Smith, Ida J.

AU - Minson, Jane B.

AU - Pilowsky, Paul M.

AU - Chalmers, John P.

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AB - 1. A quantitative electron microscopic immunocytochemical technique was used to assess the number of synapses immunoreactive for tyrosine hydroxylase (TH), phenylethanolamine N‐methyltransferase (PNMT) and neuropeptide Y (NPY) in the intermediolateral cell column in segments T2 and T3 of rat thoracic spinal cord. 2. TH synapses comprised about 5%; PNMT synapses 1–2%; and NPY synapses 1–2% of the total number of synapses in the intermediolateral cell column. All three types of synapses were predominantly or exclusively on dendrites. 3. Our results suggest that catecholamine/NPY neurons may not provide a major synaptic input to sympathetic preganglionic neurons in rat upper thoracic spinal cord.

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KW - neuropeptide Y

KW - phenylethanolamine N‐methyltransferase

KW - sympathetic preganglionic neurons

KW - tyrosine hydroxylase

KW - ultrastructure.

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THERE ARE FEW CATECHOLAMINE‐ OR NEUROPEPTIDE Y‐CONTAINING SYNAPSES IN THE INTERMEDIOLATERAL CELL COLUMN OF RAT THORACIC SPINAL CORD

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