Thromboangiitis Obliterans

Justine Smith, Manfred Zierhut

    Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


    Thromboangiitis obliterans takes its name from a paper presented in 1908 at a meeting of the Association of American Physicians. At that meeting, Leo Buerger, whose name is also attached to the disease, discussed a condition originally described by German physicians. The disease affected young adults and was characterized by thrombotic vascular occlusions of the lower limbs, with resultant ischemia that frequently led to gangrene. More recently, thromboangiitis obliterans has been defined as a “nonatherosclerotic segmental inflammatory disease that most commonly affects the small and medium-sized arteries, veins, and nerves of the arms and legs”. Although the exact prevalence is not known, the disease is rare; more cases are reported in the Middle East, the Far East, and Asia, than in the United States and Europe.
    Original languageEnglish
    Title of host publicationIntraocular Inflammation
    EditorsManfred Zierhut, Carlos Pavesio, Shigeaki Ohno, Fernando Orefice, Narsing A. Rao
    Place of PublicationBerlin
    Number of pages4
    ISBN (Electronic)9783540753872
    ISBN (Print)9783540753858
    Publication statusPublished - 2016


    • Systemic Lupus Erythematosus
    • German Physician
    • Optic Disk Edema
    • Acute Retinal Necrosis
    • Thoracic Sympathectomy


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