Tibial cartilage, subchondral bone plate and bone microarchiteture in varus- and valgus-OA vs. controls

Sophie Rapagna; Bryant Roberts; Lucian Solomon; Haoqian Qian; Karen Reynolds; Dominic Thewlis; Egon Perilli

Tibial cartilage, subchondral bone plate and bone microarchiteture in varus- and valgus-OA vs. controls

Sophie Rapagna, Bryant Roberts, Lucian Solomon, Haoqian Qian, Karen Reynolds, Dominic Thewlis, Egon Perilli

College of Science and Engineering

Research output: Contribution to conference › Paper › peer-review

Abstract

In knee osteoarthritis (OA), regional changes in proximal tibia subchondral bone plate (SBP), subchondral trabecular bone (STB) and cartilage may reflect joint loading [1, 2]. However, reports on STB and SBP differences between OA and non-pathological joints are conflicting [3, 4]. Moreover, the effect of joint alignment on cartilage morphology (thickness), the SBP and underlying STB remains unexplored [1]. This analysis aims to quantify tibia cartilage thickness, SBP thickness and STB microarchitecture in end-stage knee OA patients with varus- or valgus-aligned joints, comparing them to control (non-OA) knees.

Original language	English
Pages	436
Number of pages	1
Publication status	Published - Jul 2019
Event	25th Congress of the European Society of Biomechanics, 2019 - Vienna, Austria Duration: 7 Jul 2019 → 10 Jul 2019 Conference number: 25 https://esbiomech.org/conference/esb2019/ (Conference link)

Conference

Conference	25th Congress of the European Society of Biomechanics, 2019
Abbreviated title	ESB 2019
Country/Territory	Austria
City	Vienna
Period	7/07/19 → 10/07/19
Other	At TU Wien itself, biomechanical activities date back at least to the late 1980s and early 1990s, arising from interactions between groups from TU Wien’s Mechanical and Civil Engineering Departments and the Viennese Medical institutions. They comprise pioneering forms of bone micromechanics and adaptation modelling at the then Institute of Lightweight Design and Aerospace Engineering, or the first-ever testing device for anisotropic elasticity testing of skin, at the then Institute for Strength of Materials. In 2003, the first professor of biomechanics was appointed at TU Wien who not only established a working group in this area, but also founded the Interfacultary Laboratory for Micro- and Nanomechanics of Biological and Biomimetical Materials.
Internet address	https://esbiomech.org/conference/esb2019/ (Conference link)

Keywords

knee osteoarthritis
tibia subchondral bone plate (SBP)
tibia cartilage thickness

Cite this

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title = "Tibial cartilage, subchondral bone plate and bone microarchiteture in varus- and valgus-OA vs. controls",

abstract = "In knee osteoarthritis (OA), regional changes in proximal tibia subchondral bone plate (SBP), subchondral trabecular bone (STB) and cartilage may reflect joint loading [1, 2]. However, reports on STB and SBP differences between OA and non-pathological joints are conflicting [3, 4]. Moreover, the effect of joint alignment on cartilage morphology (thickness), the SBP and underlying STB remains unexplored [1]. This analysis aims to quantify tibia cartilage thickness, SBP thickness and STB microarchitecture in end-stage knee OA patients with varus- or valgus-aligned joints, comparing them to control (non-OA) knees. ",

keywords = "knee osteoarthritis, tibia subchondral bone plate (SBP), tibia cartilage thickness",

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pages = "436",

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TY - CONF

T1 - Tibial cartilage, subchondral bone plate and bone microarchiteture in varus- and valgus-OA vs. controls

AU - Rapagna, Sophie

AU - Roberts, Bryant

AU - Solomon, Lucian

AU - Qian, Haoqian

AU - Reynolds, Karen

AU - Thewlis, Dominic

AU - Perilli, Egon

N1 - Conference code: 25

PY - 2019/7

Y1 - 2019/7

N2 - In knee osteoarthritis (OA), regional changes in proximal tibia subchondral bone plate (SBP), subchondral trabecular bone (STB) and cartilage may reflect joint loading [1, 2]. However, reports on STB and SBP differences between OA and non-pathological joints are conflicting [3, 4]. Moreover, the effect of joint alignment on cartilage morphology (thickness), the SBP and underlying STB remains unexplored [1]. This analysis aims to quantify tibia cartilage thickness, SBP thickness and STB microarchitecture in end-stage knee OA patients with varus- or valgus-aligned joints, comparing them to control (non-OA) knees.

AB - In knee osteoarthritis (OA), regional changes in proximal tibia subchondral bone plate (SBP), subchondral trabecular bone (STB) and cartilage may reflect joint loading [1, 2]. However, reports on STB and SBP differences between OA and non-pathological joints are conflicting [3, 4]. Moreover, the effect of joint alignment on cartilage morphology (thickness), the SBP and underlying STB remains unexplored [1]. This analysis aims to quantify tibia cartilage thickness, SBP thickness and STB microarchitecture in end-stage knee OA patients with varus- or valgus-aligned joints, comparing them to control (non-OA) knees.

KW - knee osteoarthritis

KW - tibia subchondral bone plate (SBP)

KW - tibia cartilage thickness

UR - https://owncloud.tuwien.ac.at/index.php/s/dk51CU2lL9IpmWL

M3 - Paper

SP - 436

T2 - 25th Congress of the European Society of Biomechanics, 2019

Y2 - 7 July 2019 through 10 July 2019

ER -

Tibial cartilage, subchondral bone plate and bone microarchiteture in varus- and valgus-OA vs. controls

Abstract

Conference

Keywords

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