Abstract
Chiral and achiral bipyridines are readily accessible via a solvent-free Michael addition involving solid NaOH, followed by treatment with ammonium acetate in acetic acid, as a 'one pot' more benign protocol, affording pure products in high yield, typically >80%.
| Original language | English |
|---|---|
| Pages (from-to) | 2361-2363 |
| Number of pages | 3 |
| Journal | Tetrahedron Letters |
| Volume | 46 |
| Issue number | 14 |
| DOIs | |
| Publication status | Published - 4 Apr 2005 |
| Externally published | Yes |
Keywords
- Green chemistry
- Ketones
- Pyridines
- Solvent free