TY - JOUR
T1 - Traumatic Brain Injury and Depression in a Community-Based Sample
T2 - A Cohort Study Across the Adult Life Span
AU - Osborn, A. J.
AU - Mathias, J. L.
AU - Fairweather-Schmidt, A. K.
AU - Anstey, K. J.
PY - 2018/1
Y1 - 2018/1
N2 - Objectives: To determine whether self-reported traumatic brain injuries (TBIs) are associated with "cases" of clinically significant depression in the general community. To examine interactions between variables previously linked to depression after a TBI. Setting: Population-based community study (Canberra and Queanbeyan, Australia). Participants and Design: Three age cohorts: young, middle-aged, and older adults (aged 20-24, 40-44, and 60-64 years at baseline) randomly selected from the electoral roll and followed across 3 waves (4 years apart). A total of 7397, 6621, and 6042 people provided their TBI history in waves 1 to 3. Measures: Lifetime (TBI lifetime : sustained at any time since birth), recent (TBI recent : in the preceding 4 years), and multiple (TBI multiple : more than 1) TBIs, current depression, and known risk factors for depression (age, sex, marital/employment status, prior history of depression, medical conditions, recent life events, alcohol consumption, social support, physical activity). Results: Generalized estimating equations demonstrated a significant association between sustaining a TBI and experiencing clinically significant depression (cases), even after controlling for multiple demographic and health/lifestyle factors. Conclusion: There is an enduring association between depression and TBI, suggesting that, following a TBI, individuals should be monitored and supported to optimize their long-term psychological health.
AB - Objectives: To determine whether self-reported traumatic brain injuries (TBIs) are associated with "cases" of clinically significant depression in the general community. To examine interactions between variables previously linked to depression after a TBI. Setting: Population-based community study (Canberra and Queanbeyan, Australia). Participants and Design: Three age cohorts: young, middle-aged, and older adults (aged 20-24, 40-44, and 60-64 years at baseline) randomly selected from the electoral roll and followed across 3 waves (4 years apart). A total of 7397, 6621, and 6042 people provided their TBI history in waves 1 to 3. Measures: Lifetime (TBI lifetime : sustained at any time since birth), recent (TBI recent : in the preceding 4 years), and multiple (TBI multiple : more than 1) TBIs, current depression, and known risk factors for depression (age, sex, marital/employment status, prior history of depression, medical conditions, recent life events, alcohol consumption, social support, physical activity). Results: Generalized estimating equations demonstrated a significant association between sustaining a TBI and experiencing clinically significant depression (cases), even after controlling for multiple demographic and health/lifestyle factors. Conclusion: There is an enduring association between depression and TBI, suggesting that, following a TBI, individuals should be monitored and supported to optimize their long-term psychological health.
KW - community
KW - depression
KW - longitudinal
KW - multivariate
KW - population
KW - traumatic brain injury
UR - http://www.scopus.com/inward/record.url?scp=85044626904&partnerID=8YFLogxK
U2 - 10.1097/HTR.0000000000000311
DO - 10.1097/HTR.0000000000000311
M3 - Article
C2 - 28520661
SN - 0885-9701
VL - 33
SP - 62
EP - 72
JO - JOURNAL OF HEAD TRAUMA REHABILITATION
JF - JOURNAL OF HEAD TRAUMA REHABILITATION
IS - 1
ER -