TY - JOUR
T1 - Trefoil Factor Family: Unresolved Questions and Clinical Perspectives
AU - Braga Emídio, Nayara
AU - Hoffmann, Werner
AU - Brierley, Stuart M.
AU - Muttenthaler, Markus
PY - 2019
Y1 - 2019
N2 - The trefoil factor family of peptides (TFF1, TFF2, TFF3) with their lectin activities play important roles in mucosal protection and repair. However, major gaps in understanding their molecular function have hampered therapeutic development for gastrointestinal disorders. We provide here a critical overview of the status quo.
AB - The trefoil factor family of peptides (TFF1, TFF2, TFF3) with their lectin activities play important roles in mucosal protection and repair. However, major gaps in understanding their molecular function have hampered therapeutic development for gastrointestinal disorders. We provide here a critical overview of the status quo.
U2 - 10.1016/j.tibs.2019.01.004
DO - 10.1016/j.tibs.2019.01.004
M3 - Article
VL - 44
SP - 387
EP - 390
JO - Trends in Biochemical Sciences
JF - Trends in Biochemical Sciences
SN - 0968-0004
IS - 5
ER -