Trends in HIV/AIDS morbidity and mortality in Eastern Mediterranean countries, 1990–2015: findings from the Global Burden of Disease 2015 study

GBD 2015 Eastern Mediterranean Region HIV/AIDS Collaborators

doi:10.1007/s00038-017-1023-0

Trends in HIV/AIDS morbidity and mortality in Eastern Mediterranean countries, 1990–2015: findings from the Global Burden of Disease 2015 study

GBD 2015 Eastern Mediterranean Region HIV/AIDS Collaborators

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Abstract

Objectives: We used the results of the Global Burden of Disease 2015 study to estimate trends of HIV/AIDS burden in Eastern Mediterranean Region (EMR) countries between 1990 and 2015. Methods: Tailored estimation methods were used to produce final estimates of mortality. Years of life lost (YLLs) were calculated by multiplying the mortality rate by population by age-specific life expectancy. Years lived with disability (YLDs) were computed as the prevalence of a sequela multiplied by its disability weight. Results: In 2015, the rate of HIV/AIDS deaths in the EMR was 1.8 (1.4–2.5) per 100,000 population, a 43% increase from 1990 (0.3; 0.2–0.8). Consequently, the rate of YLLs due to HIV/AIDS increased from 15.3 (7.6–36.2) per 100,000 in 1990 to 81.9 (65.3–114.4) in 2015. The rate of YLDs increased from 1.3 (0.6–3.1) in 1990 to 4.4 (2.7–6.6) in 2015. Conclusions: HIV/AIDS morbidity and mortality increased in the EMR since 1990. To reverse this trend and achieve epidemic control, EMR countries should strengthen HIV surveillance, and scale up HIV antiretroviral therapy and comprehensive prevention services.

Original language	English
Pages (from-to)	123-136
Number of pages	14
Journal	International Journal of Public Health
Volume	63
Issue number	supp 1
DOIs	https://doi.org/10.1007/s00038-017-1023-0
Publication status	Published - 1 May 2018
Externally published	Yes

Bibliographical note

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Keywords

Burden of disease
Eastern Mediterranean Region
HIV
HIV mortality

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s00038-017-1023-0Licence: CC BY

2018_Article_TrendsInHIVAIDSMorbidityAndMorFinal published version, 613 KBLicence: CC BY

Cite this

@article{0887069a4b2c473fb35b0dd2f9bdfae7,

title = "Trends in HIV/AIDS morbidity and mortality in Eastern Mediterranean countries, 1990–2015: findings from the Global Burden of Disease 2015 study",

abstract = "Objectives: We used the results of the Global Burden of Disease 2015 study to estimate trends of HIV/AIDS burden in Eastern Mediterranean Region (EMR) countries between 1990 and 2015. Methods: Tailored estimation methods were used to produce final estimates of mortality. Years of life lost (YLLs) were calculated by multiplying the mortality rate by population by age-specific life expectancy. Years lived with disability (YLDs) were computed as the prevalence of a sequela multiplied by its disability weight. Results: In 2015, the rate of HIV/AIDS deaths in the EMR was 1.8 (1.4–2.5) per 100,000 population, a 43% increase from 1990 (0.3; 0.2–0.8). Consequently, the rate of YLLs due to HIV/AIDS increased from 15.3 (7.6–36.2) per 100,000 in 1990 to 81.9 (65.3–114.4) in 2015. The rate of YLDs increased from 1.3 (0.6–3.1) in 1990 to 4.4 (2.7–6.6) in 2015. Conclusions: HIV/AIDS morbidity and mortality increased in the EMR since 1990. To reverse this trend and achieve epidemic control, EMR countries should strengthen HIV surveillance, and scale up HIV antiretroviral therapy and comprehensive prevention services.",

keywords = "Burden of disease, Eastern Mediterranean Region, HIV, HIV mortality",

author = "{GBD 2015 Eastern Mediterranean Region HIV/AIDS Collaborators} and {El Bcheraoui}, Charbel and Haidong Wang and Raghid Charara and Ibrahim Khalil and Maziar Moradi-Lakeh and Ashkan Afshin and Michael Collison and Farah Daoud and Adrienne Chew and Krohn, {Kristopher J.} and Austin Carter and Foreman, {Kyle J.} and Fei He and Kassebaum, {Nicholas J.} and Michael Kutz and Mojde Mirarefin and Grant Nguyen and Naris Silpakit and Amber Sligar and Abajobir, {Amanuel A.} and Abate, {Kalkidan H.} and Abbas, {Kaja M.} and Foad Abd-Allah and Abera, {Semaw F.} and Kelemework Adane and Arnav Agarwal and Aliasghar Ahmadkiadaliri and Alireza Ahmadi and Ahmed, {Muktar B.} and {Al Lami}, {Faris H.} and Khurshid Alam and Deena Alasfoor and Reza Alizadeh-Navaei and Fatma Al-Maskari and Rajaa Al-Raddadi and Altirkawi, {Khalid A.} and Nelson Alvis-Guzman and Walid Ammar and Nahla Anber and Antonio, {Carl Abelardo T.} and Palwasha Anwari and Hamid Asayesh and Asghar, {Rana J.} and Atey, {Tesfay Mehari} and Avokpaho, {Euripide F.G.A.} and Tadesse Awokeayele and Peter Azzopardi and Umar Bacha and Aleksandra Barac and Till B{\"a}rnighausen and Shahrzad Bazargan-Hejazi and Neeraj Bedi and Bensenor, {Isabela M.} and Adugnaw Berhane and Bessong, {Pascal O.} and Beyene, {Addisu S.} and Bhutta, {Zulfiqar A.} and Charles Birungi and Butt, {Zahid A.} and Lucero Cahuana-Hurtado and Hadi Danawi and Jos{\'e} Dasneves and Kebede Deribe and Amare Deribew and {Des Jarlais}, {Don C.} and Dharmaratne, {Samath D.} and Shirin Djalalinia and Doyle, {Kerrie E.} and Endries, {Aman Y.} and Babak Eshrati and Faraon, {Emerito Jose J.A.} and Farvid, {Maryam S.} and Fereshtehnejad, {Seyed Mohammad} and Feyissa, {Tesfaye R.} and Florian Fischer and Garcia-Basteiro, {Alberto L.} and Gebrehiwot, {Tsegaye T.} and Gesesew, {Hailay A.} and Gishu, {Melkamu Dedefo D.} and Elizabeth Glaser and Gona, {Philimon N.} and Gugnani, {Harish C.} and Rahul Gupta and Hassan Haghparastbidgoli and Hailu, {Gessessew B.} and Hamadeh, {Randah R.} and Hambisa, {Mitiku T.} and Samer Hamidi and Harb, {Hilda L.} and Hareri, {Habtamu A.} and Nobuyuki Horita and Abdullatif Husseini and Ahmed Ibrahim and James, {Spencer L.} and Jonas, {Jost B.} and Amir Kasaeian and Kassaw, {Nigussie A.} and Khader, {Yousef S.} and Khan, {Ejaz A.} and Gulfaraz Khan and Khoja, {Abdullah T.A.} and Jagdish Khubchandani and Kim, {Yun Jin} and Ai Koyanagi and Barthelemy Kuatedefo and Larson, {Heidi J.} and Latif, {Asma A.} and Leshargie, {Cheru T.} and Raimundas Lunevicius and Mohammed Magdyabdalrazek and Reza Majdzadeh and Azeem Majeed and Reza Malekzadeh and Tsegahun Manyazewal and Desalegn Markos and Habibolah Masoudifarid and Alem Mehari and Mekonnen, {Alemayehu B.} and Peter Memiah and Memish, {Ziad A.} and Walter Mendoza and Mengesha, {Melkamu M.} and Mengistu, {Desalegn T.} and Mezgebe, {Haftay B.} and Mhimbira, {Francis A.} and Miller, {Ted R.} and Moore, {Ami R.} and Mumtaz, {Ghina R.} and Gopalakrishnan Natarajan and Joel Negin and Obermeyer, {Carla M.} and Ogbo, {Felix A.} and Oh, {In Hwan} and Erika Ota and Pereira, {David M.} and Farshad Pourmalek and Mostafa Qorbani and Amir Radfar and Anwar Rafay and Vafa Rahimi-Movaghar and Rai, {Rajesh Kumar} and Usha Ram and Rawaf, {David L.} and Salman Rawaf and Renzaho, {Andre M.N.} and Satar Rezaei and Rezai, {Mohammad Sadegh} and Roba, {Hirbo S.} and Gholamreza Roshandel and Mahdi Safdarian and Saeid Safiri and Sahraian, {Mohammad Ali} and Payman Salamati and Samy, {Abdallah M.} and Benn Sartorius and Sepanlou, {Sadaf G.} and Shaikh, {Masood A.} and Morteza Shamsizadeh and Sibamo, {Ephrem L.} and Singh, {Jasvinder A.} and Sobaih, {Badr H.A.} and Sergey Soshnikov and Sufiyan, {Muawiyyah B.} and Sykes, {Bryan L.} and Nuno Taveira and Tegegne, {Teketo K.} and Arash Tehrani-Banihashemi and Tesfalidet Tekelab and Girma Temamshifa and Temsah, {Mohamad Hani} and Belay Tesssema and Roman Topor-Madry and Ukwaja, {Kingsley N.} and Uthman, {Olalekan A.} and Vollset, {Stein Emil} and Fiseha Wadilo and Tolassa Wakayo and Woldu, {Minyahil A.} and Abdulhalik Workicho and Workie, {Shimelash B.} and Mohsen Yaghoubi and Yalew, {Ayalnesh Z.} and Yimam, {Hassen H.} and Naohiro Yonemoto and Yoon, {Seok Jun} and Marcel Yotebieng and Younis, {Mustafa Z.} and Zaki, {Maysaa E.S.} and Jumaan, {Aisha O.} and Theo Vos and Hay, {Simon I.} and Mohsen Naghavi and Murray, {Christopher J.L.} and Mokdad, {Ali H.}",

note = "Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.",

year = "2018",

month = may,

day = "1",

doi = "10.1007/s00038-017-1023-0",

language = "English",

volume = "63",

pages = "123--136 ",

journal = "International Journal of Public Health",

issn = "1661-8556",

publisher = "Frontiers Research Foundation",

number = "supp 1",

}

TY - JOUR

T1 - Trends in HIV/AIDS morbidity and mortality in Eastern Mediterranean countries, 1990–2015

T2 - findings from the Global Burden of Disease 2015 study

AU - GBD 2015 Eastern Mediterranean Region HIV/AIDS Collaborators

AU - El Bcheraoui, Charbel

AU - Wang, Haidong

AU - Charara, Raghid

AU - Khalil, Ibrahim

AU - Moradi-Lakeh, Maziar

AU - Afshin, Ashkan

AU - Collison, Michael

AU - Daoud, Farah

AU - Chew, Adrienne

AU - Krohn, Kristopher J.

AU - Carter, Austin

AU - Foreman, Kyle J.

AU - He, Fei

AU - Kassebaum, Nicholas J.

AU - Kutz, Michael

AU - Mirarefin, Mojde

AU - Nguyen, Grant

AU - Silpakit, Naris

AU - Sligar, Amber

AU - Abajobir, Amanuel A.

AU - Abate, Kalkidan H.

AU - Abbas, Kaja M.

AU - Abd-Allah, Foad

AU - Abera, Semaw F.

AU - Adane, Kelemework

AU - Agarwal, Arnav

AU - Ahmadkiadaliri, Aliasghar

AU - Ahmadi, Alireza

AU - Ahmed, Muktar B.

AU - Al Lami, Faris H.

AU - Alam, Khurshid

AU - Alasfoor, Deena

AU - Alizadeh-Navaei, Reza

AU - Al-Maskari, Fatma

AU - Al-Raddadi, Rajaa

AU - Altirkawi, Khalid A.

AU - Alvis-Guzman, Nelson

AU - Ammar, Walid

AU - Anber, Nahla

AU - Antonio, Carl Abelardo T.

AU - Anwari, Palwasha

AU - Asayesh, Hamid

AU - Asghar, Rana J.

AU - Atey, Tesfay Mehari

AU - Avokpaho, Euripide F.G.A.

AU - Awokeayele, Tadesse

AU - Azzopardi, Peter

AU - Bacha, Umar

AU - Barac, Aleksandra

AU - Bärnighausen, Till

AU - Bazargan-Hejazi, Shahrzad

AU - Bedi, Neeraj

AU - Bensenor, Isabela M.

AU - Berhane, Adugnaw

AU - Bessong, Pascal O.

AU - Beyene, Addisu S.

AU - Bhutta, Zulfiqar A.

AU - Birungi, Charles

AU - Butt, Zahid A.

AU - Cahuana-Hurtado, Lucero

AU - Danawi, Hadi

AU - Dasneves, José

AU - Deribe, Kebede

AU - Deribew, Amare

AU - Des Jarlais, Don C.

AU - Dharmaratne, Samath D.

AU - Djalalinia, Shirin

AU - Doyle, Kerrie E.

AU - Endries, Aman Y.

AU - Eshrati, Babak

AU - Faraon, Emerito Jose J.A.

AU - Farvid, Maryam S.

AU - Fereshtehnejad, Seyed Mohammad

AU - Feyissa, Tesfaye R.

AU - Fischer, Florian

AU - Garcia-Basteiro, Alberto L.

AU - Gebrehiwot, Tsegaye T.

AU - Gesesew, Hailay A.

AU - Gishu, Melkamu Dedefo D.

AU - Glaser, Elizabeth

AU - Gona, Philimon N.

AU - Gugnani, Harish C.

AU - Gupta, Rahul

AU - Haghparastbidgoli, Hassan

AU - Hailu, Gessessew B.

AU - Hamadeh, Randah R.

AU - Hambisa, Mitiku T.

AU - Hamidi, Samer

AU - Harb, Hilda L.

AU - Hareri, Habtamu A.

AU - Horita, Nobuyuki

AU - Husseini, Abdullatif

AU - Ibrahim, Ahmed

AU - James, Spencer L.

AU - Jonas, Jost B.

AU - Kasaeian, Amir

AU - Kassaw, Nigussie A.

AU - Khader, Yousef S.

AU - Khan, Ejaz A.

AU - Khan, Gulfaraz

AU - Khoja, Abdullah T.A.

AU - Khubchandani, Jagdish

AU - Kim, Yun Jin

AU - Koyanagi, Ai

AU - Kuatedefo, Barthelemy

AU - Larson, Heidi J.

AU - Latif, Asma A.

AU - Leshargie, Cheru T.

AU - Lunevicius, Raimundas

AU - Magdyabdalrazek, Mohammed

AU - Majdzadeh, Reza

AU - Majeed, Azeem

AU - Malekzadeh, Reza

AU - Manyazewal, Tsegahun

AU - Markos, Desalegn

AU - Masoudifarid, Habibolah

AU - Mehari, Alem

AU - Mekonnen, Alemayehu B.

AU - Memiah, Peter

AU - Memish, Ziad A.

AU - Mendoza, Walter

AU - Mengesha, Melkamu M.

AU - Mengistu, Desalegn T.

AU - Mezgebe, Haftay B.

AU - Mhimbira, Francis A.

AU - Miller, Ted R.

AU - Moore, Ami R.

AU - Mumtaz, Ghina R.

AU - Natarajan, Gopalakrishnan

AU - Negin, Joel

AU - Obermeyer, Carla M.

AU - Ogbo, Felix A.

AU - Oh, In Hwan

AU - Ota, Erika

AU - Pereira, David M.

AU - Pourmalek, Farshad

AU - Qorbani, Mostafa

AU - Radfar, Amir

AU - Rafay, Anwar

AU - Rahimi-Movaghar, Vafa

AU - Rai, Rajesh Kumar

AU - Ram, Usha

AU - Rawaf, David L.

AU - Rawaf, Salman

AU - Renzaho, Andre M.N.

AU - Rezaei, Satar

AU - Rezai, Mohammad Sadegh

AU - Roba, Hirbo S.

AU - Roshandel, Gholamreza

AU - Safdarian, Mahdi

AU - Safiri, Saeid

AU - Sahraian, Mohammad Ali

AU - Salamati, Payman

AU - Samy, Abdallah M.

AU - Sartorius, Benn

AU - Sepanlou, Sadaf G.

AU - Shaikh, Masood A.

AU - Shamsizadeh, Morteza

AU - Sibamo, Ephrem L.

AU - Singh, Jasvinder A.

AU - Sobaih, Badr H.A.

AU - Soshnikov, Sergey

AU - Sufiyan, Muawiyyah B.

AU - Sykes, Bryan L.

AU - Taveira, Nuno

AU - Tegegne, Teketo K.

AU - Tehrani-Banihashemi, Arash

AU - Tekelab, Tesfalidet

AU - Temamshifa, Girma

AU - Temsah, Mohamad Hani

AU - Tesssema, Belay

AU - Topor-Madry, Roman

AU - Ukwaja, Kingsley N.

AU - Uthman, Olalekan A.

AU - Vollset, Stein Emil

AU - Wadilo, Fiseha

AU - Wakayo, Tolassa

AU - Woldu, Minyahil A.

AU - Workicho, Abdulhalik

AU - Workie, Shimelash B.

AU - Yaghoubi, Mohsen

AU - Yalew, Ayalnesh Z.

AU - Yimam, Hassen H.

AU - Yonemoto, Naohiro

AU - Yoon, Seok Jun

AU - Yotebieng, Marcel

AU - Younis, Mustafa Z.

AU - Zaki, Maysaa E.S.

AU - Jumaan, Aisha O.

AU - Vos, Theo

AU - Hay, Simon I.

AU - Naghavi, Mohsen

AU - Murray, Christopher J.L.

AU - Mokdad, Ali H.

N1 - Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

PY - 2018/5/1

Y1 - 2018/5/1

N2 - Objectives: We used the results of the Global Burden of Disease 2015 study to estimate trends of HIV/AIDS burden in Eastern Mediterranean Region (EMR) countries between 1990 and 2015. Methods: Tailored estimation methods were used to produce final estimates of mortality. Years of life lost (YLLs) were calculated by multiplying the mortality rate by population by age-specific life expectancy. Years lived with disability (YLDs) were computed as the prevalence of a sequela multiplied by its disability weight. Results: In 2015, the rate of HIV/AIDS deaths in the EMR was 1.8 (1.4–2.5) per 100,000 population, a 43% increase from 1990 (0.3; 0.2–0.8). Consequently, the rate of YLLs due to HIV/AIDS increased from 15.3 (7.6–36.2) per 100,000 in 1990 to 81.9 (65.3–114.4) in 2015. The rate of YLDs increased from 1.3 (0.6–3.1) in 1990 to 4.4 (2.7–6.6) in 2015. Conclusions: HIV/AIDS morbidity and mortality increased in the EMR since 1990. To reverse this trend and achieve epidemic control, EMR countries should strengthen HIV surveillance, and scale up HIV antiretroviral therapy and comprehensive prevention services.

AB - Objectives: We used the results of the Global Burden of Disease 2015 study to estimate trends of HIV/AIDS burden in Eastern Mediterranean Region (EMR) countries between 1990 and 2015. Methods: Tailored estimation methods were used to produce final estimates of mortality. Years of life lost (YLLs) were calculated by multiplying the mortality rate by population by age-specific life expectancy. Years lived with disability (YLDs) were computed as the prevalence of a sequela multiplied by its disability weight. Results: In 2015, the rate of HIV/AIDS deaths in the EMR was 1.8 (1.4–2.5) per 100,000 population, a 43% increase from 1990 (0.3; 0.2–0.8). Consequently, the rate of YLLs due to HIV/AIDS increased from 15.3 (7.6–36.2) per 100,000 in 1990 to 81.9 (65.3–114.4) in 2015. The rate of YLDs increased from 1.3 (0.6–3.1) in 1990 to 4.4 (2.7–6.6) in 2015. Conclusions: HIV/AIDS morbidity and mortality increased in the EMR since 1990. To reverse this trend and achieve epidemic control, EMR countries should strengthen HIV surveillance, and scale up HIV antiretroviral therapy and comprehensive prevention services.

KW - Burden of disease

KW - Eastern Mediterranean Region

KW - HIV

KW - HIV mortality

UR - http://www.scopus.com/inward/record.url?scp=85026848284&partnerID=8YFLogxK

U2 - 10.1007/s00038-017-1023-0

DO - 10.1007/s00038-017-1023-0

M3 - Article

C2 - 28776249

AN - SCOPUS:85026848284

SN - 1661-8556

VL - 63

SP - 123

EP - 136

JO - International Journal of Public Health

JF - International Journal of Public Health

IS - supp 1

ER -

Trends in HIV/AIDS morbidity and mortality in Eastern Mediterranean countries, 1990–2015: findings from the Global Burden of Disease 2015 study

Abstract

Bibliographical note

Keywords

UN SDGs

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