TRPs as mechanosensitive channels

Greg Barritt; Grigori Rychkov

doi:10.1038/ncb0205-105

TRPs as mechanosensitive channels

Greg Barritt, Grigori Rychkov

Research output: Contribution to journal › Comment/debate

40 Citations (Scopus)

Abstract

Mechanosensitive channels are essential for effective cellular function, but elucidation of their molecular identity and mechanisms of activation has proven difficult. Two recent studies now implicate members of the transient receptor potential (TRP) family as components of the mechanosensitive channels in vertebrate hair cells (TRPA1) and stretch-activated channels (TRPC1) in several different vertebrate cell types.

Original language	English
Pages (from-to)	105-107
Number of pages	3
Journal	Nature Cell Biology
Volume	7
Issue number	2
DOIs	https://doi.org/10.1038/ncb0205-105
Publication status	Published - Feb 2005

Access to Document

10.1038/ncb0205-105Licence: In Copyright

https://search.proquest.com/docview/222369647?accountid=10910Licence: In Copyright

Cite this

@article{549911ea27f8492785135a103f10c178,

title = "TRPs as mechanosensitive channels",

abstract = "Mechanosensitive channels are essential for effective cellular function, but elucidation of their molecular identity and mechanisms of activation has proven difficult. Two recent studies now implicate members of the transient receptor potential (TRP) family as components of the mechanosensitive channels in vertebrate hair cells (TRPA1) and stretch-activated channels (TRPC1) in several different vertebrate cell types.",

author = "Greg Barritt and Grigori Rychkov",

year = "2005",

month = feb,

doi = "10.1038/ncb0205-105",

language = "English",

volume = "7",

pages = "105--107",

journal = "Nature Cell Biology",

issn = "1465-7392",

publisher = "Nature Publishing Group",

number = "2",

}

TY - JOUR

T1 - TRPs as mechanosensitive channels

AU - Barritt, Greg

AU - Rychkov, Grigori

PY - 2005/2

Y1 - 2005/2

N2 - Mechanosensitive channels are essential for effective cellular function, but elucidation of their molecular identity and mechanisms of activation has proven difficult. Two recent studies now implicate members of the transient receptor potential (TRP) family as components of the mechanosensitive channels in vertebrate hair cells (TRPA1) and stretch-activated channels (TRPC1) in several different vertebrate cell types.

AB - Mechanosensitive channels are essential for effective cellular function, but elucidation of their molecular identity and mechanisms of activation has proven difficult. Two recent studies now implicate members of the transient receptor potential (TRP) family as components of the mechanosensitive channels in vertebrate hair cells (TRPA1) and stretch-activated channels (TRPC1) in several different vertebrate cell types.

UR - http://www.scopus.com/inward/record.url?scp=13944279255&partnerID=8YFLogxK

U2 - 10.1038/ncb0205-105

DO - 10.1038/ncb0205-105

M3 - Comment/debate

C2 - 15689975

AN - SCOPUS:13944279255

SN - 1465-7392

VL - 7

SP - 105

EP - 107

JO - Nature Cell Biology

JF - Nature Cell Biology

IS - 2

ER -

TRPs as mechanosensitive channels

Abstract

Access to Document

Other files and links

Fingerprint

Cite this