TRPs as mechanosensitive channels

Greg Barritt, Grigori Rychkov

    Research output: Contribution to journalComment/debate

    35 Citations (Scopus)

    Abstract

    Mechanosensitive channels are essential for effective cellular function, but elucidation of their molecular identity and mechanisms of activation has proven difficult. Two recent studies now implicate members of the transient receptor potential (TRP) family as components of the mechanosensitive channels in vertebrate hair cells (TRPA1) and stretch-activated channels (TRPC1) in several different vertebrate cell types.

    Original languageEnglish
    Pages (from-to)105-107
    Number of pages3
    JournalNature Cell Biology
    Volume7
    Issue number2
    DOIs
    Publication statusPublished - Feb 2005

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