Tumefactive neuro-Behçet disease in a Ghanaian man

Behçet disease is most common along the ancient ‘Silk Road’ that extends from Eastern Asia to the Mediterranean. However, it can also occur in people from other ethnicities, including those from Sub-Saharan Africa. Tumour-like brain lesions are a rare manifestation of Behçet disease, and although there are no pathognomonic pathologic features, characteristic findings on brain biopsy can help confirm the diagnosis and exclude malignancy. Early intensive immunosuppression in neuro-Behçet disease can lead to favourable outcomes.

A 56-year-old Ghanaian man presented with headache and left arm weakness following a motor vehicle accident the week before...