Tunable Antibacterial Coatings That Support Mammalian Cell Growth

Krasimir Vasilev; Vasu Sah; Karine Anselme; Chi Ndi; Mihaela Mateescu; Björn Dollmann; Petr Martinek; Hardi Ys; Lydie Ploux; Hans J. Griesser

doi:10.1021/nl903274q

Tunable Antibacterial Coatings That Support Mammalian Cell Growth

Krasimir Vasilev, Vasu Sah, Karine Anselme, Chi Ndi, Mihaela Mateescu, Björn Dollmann, Petr Martinek, Hardi Ys, Lydie Ploux, Hans J. Griesser

Research output: Contribution to journal › Article › peer-review

146 Citations (Scopus)

Abstract

Bacterial infections present an enormous problem causing human suffering and cost burdens to healthcare systems worldwide. Here we present novel tunable antibacterial coatings which completely inhibit bacterial colonization by Staphylococcus epidermidis but allow normal adhesion and spreading of osteoblastic cells. The coatings are based on amine plasma polymer films loaded with silver nanoparticles. The method of preparation allows flexible control over the amount of loaded silver nanoparticles and the rate of release of silver ions.

Original language	English
Pages (from-to)	202-207
Number of pages	6
Journal	Nano Letters
Volume	10
Issue number	1
DOIs	https://doi.org/10.1021/nl903274q
Publication status	Published - 13 Jan 2010
Externally published	Yes

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AU - Vasilev, Krasimir

AU - Sah, Vasu

AU - Anselme, Karine

AU - Ndi, Chi

AU - Mateescu, Mihaela

AU - Dollmann, Björn

AU - Martinek, Petr

AU - Ys, Hardi

AU - Ploux, Lydie

AU - Griesser, Hans J.

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Y1 - 2010/1/13

N2 - Bacterial infections present an enormous problem causing human suffering and cost burdens to healthcare systems worldwide. Here we present novel tunable antibacterial coatings which completely inhibit bacterial colonization by Staphylococcus epidermidis but allow normal adhesion and spreading of osteoblastic cells. The coatings are based on amine plasma polymer films loaded with silver nanoparticles. The method of preparation allows flexible control over the amount of loaded silver nanoparticles and the rate of release of silver ions.

AB - Bacterial infections present an enormous problem causing human suffering and cost burdens to healthcare systems worldwide. Here we present novel tunable antibacterial coatings which completely inhibit bacterial colonization by Staphylococcus epidermidis but allow normal adhesion and spreading of osteoblastic cells. The coatings are based on amine plasma polymer films loaded with silver nanoparticles. The method of preparation allows flexible control over the amount of loaded silver nanoparticles and the rate of release of silver ions.

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Tunable Antibacterial Coatings That Support Mammalian Cell Growth

Abstract

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