Tuning aggregation-induced emission nanoparticle properties under thin film formation

Javad Tavakoli, Scott Pye, A. H.M.Mosinul Reza, Ni Xie, Jian Qin, Colin L. Raston, Ben Zhong Tang, Youhong Tang

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)


The most frequently used approach to preparing aggregation-induced emission fluorogen (AIEgen) particles is precipitation. Therefore, the addition of an AIEgen solution into water results in the formation of AIEgen particles in a very short time. Within such a short period of time and in the absence of proper mixing under shear, AIE particles are likely to be distributed in a wide range of sizes, thereby affecting their ultimate brightness and applications. Despite numerous attempts, the size of AIEgen particles is still within the range of 200-300 nm. For the first time, we developed a facile robust and cost-effective method for the fabrication of aggregation-induced emission nanoparticles with tuneable particle sizes <100 nm, high quantum yield, and excellent photostability. The direct diffusion of nanoparticles within the cell or in a single-celled organism, as an advantage of size reduction, opens new opportunities for biological and material studies. Such a significant reduction in AIE nanoparticle size has the potential for developing more efficient techniques for characterizing advanced nanomaterials and understanding biological processes and detection strategies.

Original languageEnglish
Pages (from-to)537-545
Number of pages10
JournalMaterials Chemistry Frontiers
Issue number2
Publication statusPublished - 1 Feb 2020


  • AIEgen
  • tuneable particle sizes
  • photostability
  • detection strategies


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