Tuning surface morphology of fluorescent hydrogels using a vortex fluidic device

Javad Tavakoli, Colin L. Raston, Youhong Tang

Research output: Contribution to journalReview articlepeer-review

Abstract

In recent decades, microfluidic techniques have been extensively used to advance hydrogel design and control the architectural features on the micro- and nanoscale. The major challenges with the microfluidic approach are clogging and limited architectural features: notably, the creation of the sphere, core-shell, and fibers. Implementation of batch production is almost impossible with the relatively lengthy time of production, which is another disadvantage. This minireview aims to introduce a new microfluidic platform, a vortex fluidic device (VFD), for one-step fabrication of hydrogels with different architectural features and properties. The application of a VFD in the fabrication of physically crosslinked hydrogels with different surface morphologies, the creation of fluorescent hydrogels with excellent photostability and fluorescence properties, and tuning of the structure–property relationship in hydrogels are discussed. We conceive, on the basis of this minireview, that future studies will provide new opportunities to develop hydrogel nanocomposites with superior properties for different biomedical and engineering applications.

Original languageEnglish
Article number3445
Number of pages13
JournalMolecules
Volume25
Issue number15
DOIs
Publication statusPublished - Aug 2020

Bibliographical note

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access
article distributed under the terms and conditions of the Creative Commons Attribution
(CC BY) license (http://creativecommons.org/licenses/by/4.0/).

Keywords

  • Aggregation-induced emission
  • Fluorescent hydrogels
  • Fluorescent property
  • Self-adhesion
  • Surface morphology
  • Vortex fluidic device

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